Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 440
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2325(2-(cyclopentylsulfanyl)-6-[1-(2,6-difluorophenyl)e...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2486(2-(cyclopentylamino)-6-[(2,6-difluorophenyl)methyl...)
Affinity DataIC50:  30nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2486(2-(cyclopentylamino)-6-[(2,6-difluorophenyl)methyl...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2321(2-(cyclopentylsulfanyl)-6-[1-(2,6-difluorophenyl)e...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2488(2-(cyclopentylamino)-6-[1-(2,6-difluorophenyl)ethy...)
Affinity DataIC50:  35nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2488(2-(cyclopentylamino)-6-[1-(2,6-difluorophenyl)ethy...)
Affinity DataIC50:  35nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2337(6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-...)
Affinity DataIC50:  40nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2487(2-(cyclopentylamino)-6-[1-(2,6-difluorophenyl)ethy...)
Affinity DataIC50:  40nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2337(6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2487(2-(cyclopentylamino)-6-[1-(2,6-difluorophenyl)ethy...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2485(2-(cyclopentylamino)-6-[(2,6-difluorophenyl)methyl...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2485(2-(cyclopentylamino)-6-[(2,6-difluorophenyl)methyl...)
Affinity DataIC50:  70nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2333(2-(cyclopentylsulfanyl)-6-[(2,6-difluorophenyl)met...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM2336(2-(cyclopentylsulfanyl)-6-[(2,6-difluorophenyl)met...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Sapienza University Of Rome

LigandPNGBDBM50004152((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory concentration required to inhibit the HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair