Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50014284
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50140281(1-{7-[3-[(3,5-Difluoro-phenyl)-ethyl-carbamoyl]-1-...)
Affinity DataIC50:  770nMAssay Description:In vitro Inhibition of apical sodium-dependent bile acid transporter by measuring the uptake of [3H]-taurocholate in hamster ileal ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50140282(1-{4-[4-((4R,5R)-3,3-Dibutyl-7-dimethylamino-4-hyd...)
Affinity DataIC50:  890nMAssay Description:In vitro Inhibition of apical sodium-dependent bile acid transporter by measuring the uptake of [3H]-taurocholate in hamster ileal ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50140280(1-{8-[3-[(3,5-Difluoro-phenyl)-ethyl-carbamoyl]-1-...)
Affinity DataIC50:  1.07E+3nMAssay Description:In vitro Inhibition of apical sodium-dependent bile acid transporter by measuring the uptake of [3H]-taurocholate in hamster ileal ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50140284((2S,3S,4S,5R)-6-[4-(3,4-Dimethoxy-phenyl)-2-(3-eth...)
Affinity DataIC50:  2.80E+3nMAssay Description:In vitro Inhibition of apical sodium-dependent bile acid transporter by measuring the uptake of [3H]-taurocholate in hamster ileal ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50140283((4R,5R)-3,3-Dibutyl-7-dimethylamino-5-(4-methoxy-p...)
Affinity DataIC50: >6.30E+4nMAssay Description:In vitro Inhibition of apical sodium-dependent bile acid transporter by measuring the uptake of [3H]-taurocholate in hamster ileal ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50085476(1-(3,4-Dimethoxy-phenyl)-3-(3-ethyl-pentanoyl)-4-h...)
Affinity DataIC50: >1.85E+5nMAssay Description:In vitro Inhibition of apical sodium-dependent bile acid transporter by measuring the uptake of [3H]-taurocholate in hamster ileal ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed