Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50035384
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145324((2-m-Tolyl-ethyl)-[6-(3-trifluoromethyl-[1,2,4]tri...)
Affinity DataIC50:  15nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145330(CHEMBL310121 | [2-(3-Bromo-phenyl)-ethyl]-{(S)-1-[...)
Affinity DataIC50:  28nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145307((2-m-Tolyl-ethyl)-{1-[6-(3-trifluoromethyl-[1,2,4]...)
Affinity DataIC50:  29nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145305(CHEMBL446627 | Phenethyl-{(S)-1-[6-(3-trifluoromet...)
Affinity DataIC50:  30nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366906(CHEMBL1169381)
Affinity DataIC50:  30nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145329(CHEMBL79184 | Phenethyl-{1-[6-(3-trifluoromethyl-[...)
Affinity DataIC50:  36nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145306(CHEMBL84067 | Phenethyl-[6-(3-trifluoromethyl-[1,2...)
Affinity DataIC50:  72nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145326(CHEMBL311873 | [2-(3-Methoxy-phenyl)-ethyl]-[6-(3-...)
Affinity DataIC50:  116nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145313(CHEMBL81850 | [6-(3-Methoxymethyl-[1,2,4]triazolo[...)
Affinity DataIC50:  131nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145314(CHEMBL81225 | [6-(3-Methyl-[1,2,4]triazolo[3,4-a]p...)
Affinity DataIC50:  145nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145316(CHEMBL79968 | [6-(3-Cyclohexyl-[1,2,4]triazolo[3,4...)
Affinity DataIC50:  145nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145311(CHEMBL79762 | [2-(3-Fluoro-phenyl)-ethyl]-[6-(3-tr...)
Affinity DataIC50:  161nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145331(CHEMBL309198 | {2-Methyl-1-[6-(3-trifluoromethyl-[...)
Affinity DataIC50:  174nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145328(CHEMBL81495 | Phenethyl-{1-[6-(3-trifluoromethyl-[...)
Affinity DataIC50:  183nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145322(CHEMBL79400 | [6-(3-Methylsulfanyl-[1,2,4]triazolo...)
Affinity DataIC50:  194nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145301(CHEMBL310209 | Phenethyl-[6-(3-phenyl-[1,2,4]triaz...)
Affinity DataIC50:  195nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145302((2-Phenyl-propyl)-[6-(3-trifluoromethyl-[1,2,4]tri...)
Affinity DataIC50:  198nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145327(CHEMBL81141 | {6-[3-(5-Methyl-isoxazol-3-yl)-[1,2,...)
Affinity DataIC50:  220nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145319((R)-((S)-2-Phenyl-cyclopropyl)-[6-(3-trifluorometh...)
Affinity DataIC50:  229nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145299(CHEMBL79423 | Phenethyl-[6-([1,2,4]triazolo[3,4-a]...)
Affinity DataIC50:  230nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145318(CHEMBL418920 | [6-(3-Ethyl-[1,2,4]triazolo[3,4-a]p...)
Affinity DataIC50:  241nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145303((2-p-Tolyl-ethyl)-[6-(3-trifluoromethyl-[1,2,4]tri...)
Affinity DataIC50:  260nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145304(CHEMBL82891 | [6-(3-Cyclopropyl-[1,2,4]triazolo[3,...)
Affinity DataIC50:  272nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145321(CHEMBL79618 | [2-(2-Fluoro-phenyl)-ethyl]-[6-(3-tr...)
Affinity DataIC50:  291nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145317(CHEMBL81851 | [6-(3-Isopropyl-[1,2,4]triazolo[3,4-...)
Affinity DataIC50:  342nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145308((2-o-Tolyl-ethyl)-[6-(3-trifluoromethyl-[1,2,4]tri...)
Affinity DataIC50:  448nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145300(CHEMBL420593 | [2-(4-Fluoro-phenyl)-ethyl]-[6-(3-t...)
Affinity DataIC50:  630nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145325(((S)-1-Methyl-2-phenyl-ethyl)-[6-(3-trifluoromethy...)
Affinity DataIC50:  700nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145309(CHEMBL315485 | [2-(4-Methoxy-phenyl)-ethyl]-[6-(3-...)
Affinity DataIC50:  829nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145312((1-Methyl-2-phenyl-ethyl)-[6-(3-trifluoromethyl-[1...)
Affinity DataIC50:  1.37E+3nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145310(CHEMBL309390 | [2-(2-Methoxy-phenyl)-ethyl]-[6-(3-...)
Affinity DataIC50:  3.16E+3nMAssay Description:Binding affinity against alpha-2 delta-1 subunit of voltage gated subunit of Ca+2 channel in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145323(CHEMBL83372 | Phenethyl-{(R)-1-[6-(3-trifluorometh...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145315((1,1-Dimethyl-2-phenyl-ethyl)-[6-(3-trifluoromethy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50145320(CHEMBL315405 | Methyl-phenethyl-[6-(3-trifluoromet...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity against alpha2 delta-1 subunit of voltage-gated calcium channel in human.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed