Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50035404
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148704((6-Chloro-2-methyl-3H-benzoimidazol-5-yl)-[4-(2,4-...)
Affinity DataIC50:  700nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148720(CHEMBL120160 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibit of human Met proto-oncogene tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148716(CHEMBL334158 | [5-(3-Amino-3-methyl-but-1-ynyl)-2-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148711(CHEMBL121512 | [5-(3-Amino-3-methyl-but-1-ynyl)-2-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148715((6-Chloro-2-methyl-3H-benzoimidazol-5-yl)-[6-(2,4-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibit of human c-Jun N-terminal kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibit of human c-Jun N-terminal kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148707((2-Chloro-phenyl)-[4-(2,4-difluoro-phenylamino)-ph...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148706(CHEMBL332738 | [5-(3-Amino-3-methyl-but-1-ynyl)-2-...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148705(CHEMBL334248 | [6-(2,4-Difluoro-phenylamino)-pyrid...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148712(CHEMBL120127 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148718(CHEMBL332342 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148713(CHEMBL120317 | [6-(2,4-Difluoro-phenylamino)-pyrid...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148717((2-Chloro-phenyl)-[6-(2,4-difluoro-phenylamino)-py...)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148721(CHEMBL121508 | [5-(3-Amino-3-methyl-butyl)-2-metho...)
Affinity DataIC50:  1.13E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148719(CHEMBL120175 | [5-(3-Amino-3-methyl-butyl)-2-chlor...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148710((5-Bromo-2-chloro-phenyl)-[6-(2,4-difluoro-phenyla...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148714(CHEMBL120128 | [6-(2,4-Difluoro-phenylamino)-pyrid...)
Affinity DataIC50:  4.79E+5nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed