Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50014956
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50054245(5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N''...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149518(CHEMBL182752 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  13nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149515(CHEMBL181593 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  15nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149528(CHEMBL359925 | Cyclopropylmethyl-[2-methyl-6-(2,4,...)
Affinity DataKi:  26nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149529(CHEMBL182706 | [5-Allyl-6-(cyclopropylmethyl-propy...)
Affinity DataKi:  31nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149521(CHEMBL182643 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  38nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149526((6-Diallylamino-2,5-dimethyl-pyrimidin-4-yl)-(2,4,...)
Affinity DataKi:  38nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149533(CHEMBL184851 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  55nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149522((6-Dipropylamino-2,5-dimethyl-pyrimidin-4-yl)-(2,4...)
Affinity DataKi:  58nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149541(CHEMBL360128 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  79nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149532(CHEMBL361831 | Cyclopropylmethyl-{6-[methoxy-(2,4,...)
Affinity DataKi:  90nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149520(CHEMBL362224 | [2,5-Dimethyl-6-(phenyl-propyl-amin...)
Affinity DataKi:  180nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149540(CHEMBL360845 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  200nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149513(CHEMBL181439 | [6-(1-Ethyl-propylamino)-2,5-dimeth...)
Affinity DataKi:  220nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149539(CHEMBL359745 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  360nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149519(CHEMBL184963 | [6-((S)-2-Methoxymethyl-pyrrolidin-...)
Affinity DataKi:  380nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149534(CHEMBL182825 | [6-(Ethyl-phenyl-amino)-2,5-dimethy...)
Affinity DataKi:  470nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149530(CHEMBL364117 | Cyclopropylmethyl-{2-methyl-6-[1-(2...)
Affinity DataKi:  480nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149536(CHEMBL369717 | {6-[(2-Hydroxy-ethyl)-propyl-amino]...)
Affinity DataKi:  540nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149517(CHEMBL359636 | Cyclopropylmethyl-{2-methyl-6-[1-(2...)
Affinity DataKi:  560nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149538(CHEMBL182500 | [4-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  630nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149527(CHEMBL369333 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  810nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149537(CHEMBL182803 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  810nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149531(CHEMBL185400 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149525(CHEMBL362226 | {6-[Bis-(2-methoxy-ethyl)-amino]-2,...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149524(CHEMBL183037 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149535(1-[6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyr...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149542(CHEMBL182705 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi:  5.10E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149516((2,5-Dimethyl-6-pyrrolidin-1-yl-pyrimidin-4-yl)-(2...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149512(CHEMBL360455 | Cyclopropylmethyl-{2-methyl-6-[1-me...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149514((2,5-Dimethyl-6-morpholin-4-yl-pyrimidin-4-yl)-(2,...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149523(CHEMBL180845 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149521(CHEMBL182643 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149515(CHEMBL181593 | [6-(Cyclopropylmethyl-propyl-amino)...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed