Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 566
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3900((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  72nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3893((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  78nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3902((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  85nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3903((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  99nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3895((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  100nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3908((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  340nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3897((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  420nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3901((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  430nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3894((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  440nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3896((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  480nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3904((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  490nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3899((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  490nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3886((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-2-({[(2H-1,3-ben...)
Affinity DataIC50:  500nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3885((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-2-{[(benzylcarba...)
Affinity DataIC50:  590nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3881((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  600nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3891((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  710nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3890(Azapeptide-based compound 31)
Affinity DataIC50:  800nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3898((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  860nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3906((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  2.40E+3nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3905((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  4.10E+3nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3889((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-2-{[(benzylcarba...)
Affinity DataIC50:  4.20E+3nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3892((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  4.30E+3nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3888((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  4.40E+3nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3907((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  5.70E+3nMAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3880((2S)-2-{[(2S,4R)-4-(benzyloxy)-1-[(2S)-2-[(2S)-2-[...)
Affinity DataIC50:  7.00E+3nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3887((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-2-({[benzyl(meth...)
Affinity DataIC50:  8.40E+3nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3884((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  1.75E+4nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3883((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  2.60E+4nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3882((4R)-4-{[(1S)-1-{[(2S)-1-[(2S,4R)-4-(benzyloxy)-2-...)
Affinity DataIC50:  3.40E+4nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1027-1206,R1052K]/[1678-1691](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM3879((2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(3S)-3-[(3S)-3-ac...)
Affinity DataIC50:  1.50E+5nMpH: 7.5 T: 2°CAssay Description:The enzymatic assay was performed in assay buffer containing the enzyme complex (protease and NS4A-derived peptide), substrate DDIVPCSMSYTW/biotin-DD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed