Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 50036039
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50455629(CHEMBL487720)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50455629(CHEMBL487720)
Affinity DataIC50:  12nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50406129(CHEMBL175236)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50004776(CHEMBL323880 | Sodium; 3,5-dihydroxy-7-[6-hydroxy-...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50406129(CHEMBL175236)
Affinity DataIC50:  29nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)
Affinity DataIC50:  37nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50004775(2-Methyl-butyric acid 3-hydroxy-8-[2-(4-hydroxy-6-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50004776(CHEMBL323880 | Sodium; 3,5-dihydroxy-7-[6-hydroxy-...)
Affinity DataIC50:  2.22E+3nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed