Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 50015169
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152565(4-(4-Chloro-4''-methoxy-biphenyl-3-yl)-2,4-dioxo-b...)
Affinity DataIC50:  190nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152557(2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...)
Affinity DataIC50:  310nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152558(4-(4-Chloro-biphenyl-3-yl)-2,4-dioxo-butyric acid ...)
Affinity DataIC50:  330nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152562(4-(3,4''-Dichloro-biphenyl-4-yl)-2,4-dioxo-butyric...)
Affinity DataIC50:  410nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152557(2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...)
Affinity DataIC50:  440nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152553(4-[5-(4-Chloro-3-fluoro-phenyl)-thiophen-2-yl]-2,4...)
Affinity DataIC50:  570nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152565(4-(4-Chloro-4''-methoxy-biphenyl-3-yl)-2,4-dioxo-b...)
Affinity DataIC50:  570nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152553(4-[5-(4-Chloro-3-fluoro-phenyl)-thiophen-2-yl]-2,4...)
Affinity DataIC50:  900nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152564(4-[5-(4-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  980nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152558(4-(4-Chloro-biphenyl-3-yl)-2,4-dioxo-butyric acid ...)
Affinity DataIC50:  1.13E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152581(4-(4''-Methoxy-biphenyl-3-yl)-2,4-dioxo-butyric ac...)
Affinity DataIC50:  1.36E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152580(4-[5-(4-Ethoxy-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  1.40E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152567(2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...)
Affinity DataIC50:  1.52E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152581(4-(4''-Methoxy-biphenyl-3-yl)-2,4-dioxo-butyric ac...)
Affinity DataIC50:  1.59E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152559(4-Biphenyl-4-yl-2,4-dioxo-butyric acid | CHEMBL182...)
Affinity DataIC50:  1.60E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152563(2,4-Dioxo-4-(5-phenyl-furan-2-yl)-butyric acid | C...)
Affinity DataIC50:  1.66E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50115581((Z)-2-Hydroxy-4-oxo-4-(4-phenoxy-phenyl)-but-2-eno...)
Affinity DataIC50:  1.75E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152562(4-(3,4''-Dichloro-biphenyl-4-yl)-2,4-dioxo-butyric...)
Affinity DataIC50:  1.77E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152563(2,4-Dioxo-4-(5-phenyl-furan-2-yl)-butyric acid | C...)
Affinity DataIC50:  1.81E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152577(4-(2,5-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50:  1.82E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152551(4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  1.85E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152572(2,4-Dioxo-4-(5-phenyl-thiophen-2-yl)-butyric acid ...)
Affinity DataIC50:  1.85E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50115581((Z)-2-Hydroxy-4-oxo-4-(4-phenoxy-phenyl)-but-2-eno...)
Affinity DataIC50:  1.87E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152567(2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...)
Affinity DataIC50:  2.32E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152566(4-[5-(4-tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-b...)
Affinity DataIC50:  3.13E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152548(4-Biphenyl-3-yl-2,4-dioxo-butyric acid | CHEMBL185...)
Affinity DataIC50:  3.24E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152559(4-Biphenyl-4-yl-2,4-dioxo-butyric acid | CHEMBL182...)
Affinity DataIC50:  3.50E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152554(4-(2-Chloro-phenyl)-2,4-dioxo-butyric acid | CHEMB...)
Affinity DataIC50:  3.51E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152548(4-Biphenyl-3-yl-2,4-dioxo-butyric acid | CHEMBL185...)
Affinity DataIC50:  3.62E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152569(2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid | CHEM...)
Affinity DataIC50:  5.44E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152568(4-(2,4-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50:  5.53E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50083940(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)
Affinity DataIC50:  6.96E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152577(4-(2,5-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50:  7.00E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152569(2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid | CHEM...)
Affinity DataIC50:  7.31E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152572(2,4-Dioxo-4-(5-phenyl-thiophen-2-yl)-butyric acid ...)
Affinity DataIC50:  7.65E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152568(4-(2,4-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50:  9.85E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152574(2,4-Dioxo-4-thiophen-2-yl-butyric acid | CHEMBL183...)
Affinity DataIC50:  1.01E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152564(4-[5-(4-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  1.08E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152580(4-[5-(4-Ethoxy-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  1.13E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152551(4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)
Affinity DataIC50:  1.22E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50083934(4-(4-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)
Affinity DataIC50:  1.27E+4nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152575(2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...)
Affinity DataIC50:  1.29E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50083940(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)
Affinity DataIC50:  1.31E+4nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152566(4-[5-(4-tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-b...)
Affinity DataIC50:  1.35E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152579(4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid | CHEMB...)
Affinity DataIC50:  1.45E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152552(4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50:  1.77E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50083934(4-(4-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)
Affinity DataIC50:  1.93E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152552(4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50:  2.21E+4nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50115579((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)
Affinity DataIC50:  2.49E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152570((8-Hydroxy-[1,6]naphthyridin-7-yl)-(4-phenoxy-phen...)
Affinity DataIC50:  2.90E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 72 total ) | Next | Last >>
Jump to: