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Found 12 Enz. Inhib. hit(s) with all data for entry = 1185
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9745((4S)-4-{[(1S)-3-carboxy-1-{[(1S)-1-{[(2S)-1-[(5S)-...)
Affinity DataKi:  310nM ΔG°:  -37.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9743((4S)-4-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(5S)-3-benzyl-2...)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9741((4S)-4-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(5S)-3-benzyl-2...)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9737((4S)-4-{[(1S)-3-carboxy-1-{[(1S)-1-{[(2S)-1-[(5S)-...)
Affinity DataKi:  4.00E+3nM ΔG°:  -31.3kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9736(2-oxoimidazolidine-4-carboxylic acid deriv. 14a | ...)
Affinity DataKi:  3.00E+4nM ΔG°:  -26.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9735((4S)-4-{[(1S)-3-carboxy-1-{[(1S)-2-methyl-1-{[(2S)...)
Affinity DataKi:  4.60E+4nM ΔG°:  -25.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9740(2-oxoimidazolidine-4-carboxylic acid deriv. 14b | ...)
Affinity DataKi:  6.10E+4nM ΔG°:  -24.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9734(2-oxoimidazolidine-4-carboxylic acid deriv. 7 | te...)
Affinity DataKi:  6.90E+4nM ΔG°:  -24.1kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9738(2-oxoimidazolidine-4-carboxylic acid deriv. 16 | e...)
Affinity DataKi:  7.80E+4nM ΔG°:  -23.8kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9742(2-oxoimidazolidine-4-carboxylic acid deriv. 14bb |...)
Affinity DataKi: >1.00E+5nM ΔG°: >-23.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9744(2-oxoimidazolidine-4-carboxylic acid deriv. 14c | ...)
Affinity DataKi: >1.00E+5nM ΔG°: >-23.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9739(2-oxoimidazolidine-4-carboxylic acid deriv. 17 | e...)
Affinity DataKi:  1.50E+5nM ΔG°:  -22.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed