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Found 24 Enz. Inhib. hit(s) with all data for entry = 50015466
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156313(4-[3-(3-{2-[1-(2-Methoxy-phenyl)-piperidin-4-ylami...)
Affinity DataKi:  1.90nMAssay Description:Antagonist activity towards Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156311(CHEMBL187620 | N-arylpiperazine derivative)
Affinity DataKi:  3.60nMAssay Description:Antagonist activity towards Neuropeptide Y receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156328(2,6-Dimethyl-4-[3-(3-{2-[1-(2-nitro-phenyl)-piperi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156313(4-[3-(3-{2-[1-(2-Methoxy-phenyl)-piperidin-4-ylami...)
Affinity DataIC50:  2nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156319(2,6-Dimethyl-4-(3-{3-[2-(1-phenyl-piperidin-4-ylam...)
Affinity DataIC50:  2nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156323(CHEMBL189412 | N-arylpiperazine derivative)
Affinity DataIC50:  3nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156317(CHEMBL187925 | N-arylpiperazine derivative)
Affinity DataIC50:  3nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156326(4-[3-(3-{2-[1-(2-Cyano-phenyl)-piperidin-4-ylamino...)
Affinity DataIC50:  3nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156331(2,6-Dimethyl-4-(3-{3-[2-(1-o-tolyl-piperidin-4-yla...)
Affinity DataIC50:  4nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156316(CHEMBL188576 | N-arylpiperazine derivative)
Affinity DataIC50:  4nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156318(CHEMBL361273 | N-arylpiperazine derivative)
Affinity DataIC50:  4nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156311(CHEMBL187620 | N-arylpiperazine derivative)
Affinity DataIC50:  4nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156314(CHEMBL364380 | N-arylpiperazine derivative)
Affinity DataIC50:  5nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156322(2,6-Dimethyl-4-[3-(3-{2-[1-(2-methylsulfanyl-pheny...)
Affinity DataIC50:  5nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156312(4-[3-(3-{2-[1-(2-Hydroxy-phenyl)-piperidin-4-ylami...)
Affinity DataIC50:  6nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156321(CHEMBL187490 | N-arylpiperazine derivative)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156315(4-[3-(3-{2-[1-(3-Chloro-phenyl)-piperidin-4-ylamin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156325(CHEMBL188790 | N-arylpiperazine derivative)
Affinity DataIC50:  10nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109185(4-[3-(3-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataIC50:  12nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156327(CHEMBL189036 | N-arylpiperazine derivative)
Affinity DataIC50:  14nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156324(2,6-Dimethyl-4-[3-(3-{2-[1-(2-trifluoromethoxy-phe...)
Affinity DataIC50:  25nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156329(CHEMBL187782 | N-arylpiperazine derivative)
Affinity DataIC50:  28nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156320(2,6-Dimethyl-4-[3-(3-{2-[1-(2-trifluoromethyl-phen...)
Affinity DataIC50:  31nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156330(BMS-245782 | CHEMBL189548 | N-arylpiperazine deriv...)
Affinity DataIC50:  39nMAssay Description:Inhibition of binding of [125I]-PYY to membranes of SK-N-MC cells expressing the human Y1 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed