Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50015839
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161488(CHEMBL439289 | Des-His1[Glu9]glucagon-NH2)
Affinity DataIC50:  18nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161488(CHEMBL439289 | Des-His1[Glu9]glucagon-NH2)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410091(CHEMBL2112992)
Affinity DataIC50:  34nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161498(4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophen...)
Affinity DataIC50:  41nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161497(CHEMBL178768 | N-{3-Cyano-6-[(2,4-dichloro-benzyl)...)
Affinity DataIC50:  59nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161496(CHEMBL179181 | N-{3-Cyano-6-[(2,4-dichloro-benzyl)...)
Affinity DataIC50:  63nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410091(CHEMBL2112992)
Affinity DataIC50:  89nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161496(CHEMBL179181 | N-{3-Cyano-6-[(2,4-dichloro-benzyl)...)
Affinity DataIC50:  92nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161497(CHEMBL178768 | N-{3-Cyano-6-[(2,4-dichloro-benzyl)...)
Affinity DataIC50:  129nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161494(CHEMBL179281 | N-[3-Cyano-6-(1,1-dimethyl-propyl)-...)
Affinity DataIC50:  129nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(CHEMBL182148 | N-{3-Cyano-6-[methyl-(1,2,3,4-tetra...)
Affinity DataIC50:  139nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(CHEMBL182148 | N-{3-Cyano-6-[methyl-(1,2,3,4-tetra...)
Affinity DataIC50:  139nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161498(4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophen...)
Affinity DataIC50:  153nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(CHEMBL182148 | N-{3-Cyano-6-[methyl-(1,2,3,4-tetra...)
Affinity DataIC50:  158nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(CHEMBL182148 | N-{3-Cyano-6-[methyl-(1,2,3,4-tetra...)
Affinity DataIC50:  158nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161494(CHEMBL179281 | N-[3-Cyano-6-(1,1-dimethyl-propyl)-...)
Affinity DataIC50:  181nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410090(CHEMBL2112991)
Affinity DataIC50:  185nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50410090(CHEMBL2112991)
Affinity DataIC50:  368nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161492(6-(1,1-Dimethyl-propyl)-2-(2-ethyl-butyrylamino)-4...)
Affinity DataIC50:  870nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161495(CHEMBL178302 | N-[3-Cyano-5-(5-isobutyl-[1,3,4]oxa...)
Affinity DataIC50:  3.21E+3nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161490(CHEMBL181669 | N-[6-(Benzyl-methyl-amino)-3-cyano-...)
Affinity DataIC50:  3.82E+3nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161499(4-Bromo-N-[3-cyano-6-(1,1-dimethyl-propyl)-4,5,6,7...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration towards binding of [125I]-glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed