Affinity DataIC50: 6nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]NDP-a...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 5 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]NDP-a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]NDP-a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition concentration (binding affinity) against mouse melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition concentration (binding affinity) against rat melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors expr...More data for this Ligand-Target Pair
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 5 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition concentration (binding affinity) against dog melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors expr...More data for this Ligand-Target Pair
Affinity DataIC50: 9.87E+3nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]NDP-a...More data for this Ligand-Target Pair
TargetAdrenocorticotropic hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 2 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 1 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 9.42E+5nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataIC50: 9.45E+5nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 5 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
Affinity DataEC50: 850nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 165nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP-...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+5nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]-NDP-...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 3 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+5nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation in human melanocortin receptor (hMC5R)More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation in human melanocortin receptor (hMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation in dog melanocortin receptor (dMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation in rat melanocortin receptor (rMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 1.98E+3nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.60E+5nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation in human melanocortin receptor (hMC1R)More data for this Ligand-Target Pair
Affinity DataEC50: 238nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+5nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]-NDP-...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP-...More data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation in mouse melanocortin receptor (mMC4R)More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.60E+5nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 1 by radio labeled ligand assay (Displacement of [125I]-NDP-...More data for this Ligand-Target Pair