Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 1197
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9911(3-Phenyl-7-(4-biphenylmethoxy)-2-[(4-pyridylmethyl...)
Affinity DataKi:  39nM ΔG°:  -44.0kJ/mole IC50:  79nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9903(3-Phenyl-7-(beta-naphthylmethoxy)-2-[(4-pyridylmet...)
Affinity DataKi:  74nM ΔG°:  -42.3kJ/mole IC50:  90nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9902(3-Phenyl-7-(alpha-naphthylmethoxy)-2-[(4-pyridylme...)
Affinity DataKi:  114nM ΔG°:  -41.2kJ/mole IC50:  112nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50:  2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9900(3-Phenyl-7-(3-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  113nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9901(3-Phenyl-7-(4-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  132nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9899(3-Phenyl-7-(2-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  138nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9906(3-Phenyl-7-(4-methoxyphenylmethoxy)-2-[(4-pyridylm...)
Affinity DataIC50:  161nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9909(3-Phenyl-7-(4-bromophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50:  213nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9910(3-Phenyl-7-(4-chlorophenylmethoxy)-2-[(4-pyridylme...)
Affinity DataIC50:  233nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9905(3-Phenyl-7-(2-methoxyphenylmethoxy)-2-[(4-pyridylm...)
Affinity DataIC50:  243nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9908(3-Phenyl-7-(4-fluorophenylmethoxy)-2-[(4-pyridylme...)
Affinity DataIC50:  337nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9904(3-Phenyl-7-(phenylethoxy)-2-[(4-pyridylmethyl)thio...)
Affinity DataIC50:  359nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9912(3-Phenyl-7-(2-pyridylmethoxy)-2-[(4-pyridylmethyl)...)
Affinity DataIC50:  378nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9907(3-Phenyl-7-(cyclohexylmethoxy)-2-[(4-pyridylmethyl...)
Affinity DataIC50:  553nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed