Compile Data Set for Download or QSAR
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Found 14 Enz. Inhib. hit(s) with all data for entry = 50016946
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175652(CHEMBL200667 | Dodecanoic acid (S)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  80nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175656(CHEMBL200398 | Dodecanoic acid (S)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  160nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175653(CHEMBL200140 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  250nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175651(CHEMBL382272 | Dodecanoic acid (R)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  350nMAssay Description:Antagonistic potency at human TLR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175650(CHEMBL383597 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  900nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175655(CHEMBL372577 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  950nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175654(CHEMBL190383 | Tetradecanoic acid (R)-2-({2-[2-car...)
Affinity DataIC50:  1.25E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175651(CHEMBL382272 | Dodecanoic acid (R)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonistic activity at TLR in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175658(CHEMBL200206 | Dodecanoic acid (R)-1-{2-[(R)-3-(hy...)
Affinity DataIC50:  2.15E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175651(CHEMBL382272 | Dodecanoic acid (R)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  3.07E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175657(CHEMBL380585 | N-(2-{[(R)-3-((R)-3-Dodecanoylamino...)
Affinity DataIC50:  5.20E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175656(CHEMBL200398 | Dodecanoic acid (S)-1-{2-[(R)-3-({2...)
Affinity DataIC50:  6.46E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175652(CHEMBL200667 | Dodecanoic acid (S)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  6.90E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50175653(CHEMBL200140 | Dodecanoic acid (R)-1-{2-[(S)-3-({2...)
Affinity DataIC50:  2.20E+4nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed