Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 1737
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13778(2-[3-(5-carbamimidoyl-1H-indol-2-yl)-4-hydroxy-5-(...)
Affinity DataKi:  4nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13776(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-4-h...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13786(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  20nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM13778(2-[3-(5-carbamimidoyl-1H-indol-2-yl)-4-hydroxy-5-(...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13787(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  62nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13781(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  300nM ΔG°:  -36.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM13776(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-4-h...)
Affinity DataKi:  320nM ΔG°:  -36.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13778(2-[3-(5-carbamimidoyl-1H-indol-2-yl)-4-hydroxy-5-(...)
Affinity DataKi:  400nM ΔG°:  -36.2kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13788(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-5-{3-...)
Affinity DataKi:  1.40E+3nM ΔG°:  -33.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13782(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  2.40E+3nM ΔG°:  -31.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13784(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  2.50E+3nM ΔG°:  -31.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM13778(2-[3-(5-carbamimidoyl-1H-indol-2-yl)-4-hydroxy-5-(...)
Affinity DataKi:  2.90E+3nM ΔG°:  -31.3kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM13781(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  3.50E+3nM ΔG°:  -30.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13783(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  7.40E+3nM ΔG°:  -29.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13776(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-4-h...)
Affinity DataKi:  1.10E+4nM ΔG°:  -28.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13779(2-[3-(1H-1,3-benzodiazol-2-yl)-4-hydroxy-5-(3-nitr...)
Affinity DataKi:  1.10E+4nM ΔG°:  -28.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13785(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-5-[3-...)
Affinity DataKi:  1.20E+4nM ΔG°:  -27.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM13780(2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  3.90E+4nM ΔG°:  -24.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM13781(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  4.40E+4nM ΔG°:  -24.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13781(2-(3-{5-amino-1H-pyrrolo[3,2-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi:  1.20E+5nM ΔG°:  -22.2kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13780(2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13779(2-[3-(1H-1,3-benzodiazol-2-yl)-4-hydroxy-5-(3-nitr...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM13780(2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM13779(2-[3-(1H-1,3-benzodiazol-2-yl)-4-hydroxy-5-(3-nitr...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM13776(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-4-h...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM13779(2-[3-(1H-1,3-benzodiazol-2-yl)-4-hydroxy-5-(3-nitr...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM13780(2-(3-{5-amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hyd...)
Affinity DataKi: >1.50E+5nM ΔG°: >-21.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed