Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 50017577
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184105(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  1.01nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184109(4'-trifluoromethyl-biphenyl-2-carboxylic acid {2-m...)
Affinity DataIC50:  1.64nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184153(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  1.68nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184111(4'-trifluoromethyl-biphenyl-2-carboxylic acid [2-m...)
Affinity DataIC50:  1.75nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184165(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  1.78nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184118(4'-trifluoromethyl-biphenyl-2-carboxylic acid {2-m...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184137(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  2.34nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184127(CHEMBL207443 | N-((S)-Phenyl-propylcarbamoyl-methy...)
Affinity DataIC50:  2.53nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184152(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-[(...)
Affinity DataIC50:  2.97nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184138(4'-trifluoromethyl-biphenyl-2-carboxylic acid [2-m...)
Affinity DataIC50:  3.37nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184147(4'-trifluoromethyl-biphenyl-2-carboxylic acid {4-[...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184104(4'-trifluoromethyl-biphenyl-2-carboxylic acid {4-[...)
Affinity DataIC50:  3.85nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184130(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-{[...)
Affinity DataIC50:  4.11nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184139(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  4.62nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184124(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-{[...)
Affinity DataIC50:  5.05nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184141(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  5.28nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184160(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...)
Affinity DataIC50:  5.53nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184166(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-((...)
Affinity DataIC50:  5.67nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184112(4'-trifluoromethyl-biphenyl-2-carboxylic acid [3-m...)
Affinity DataIC50:  6.23nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184100(4'-trifluoromethyl-biphenyl-2-carboxylic acid [2-m...)
Affinity DataIC50:  6.38nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184148(4'-trifluoromethyl-biphenyl-2-carboxylic acid [3-m...)
Affinity DataIC50:  6.47nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184110(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  7.14nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184123(4'-trifluoromethyl-biphenyl-2-carboxylic acid [4-(...)
Affinity DataIC50:  7.33nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184129(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-((...)
Affinity DataIC50:  8.15nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184120(4'-trifluoromethyl-biphenyl-2-carboxylic acid {4-[...)
Affinity DataIC50:  8.27nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184125(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-piperid...)
Affinity DataIC50:  9.43nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184102(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-((...)
Affinity DataIC50:  11.8nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184121(CHEMBL410089 | N-[(S)-(benzyl-methyl-carbamoyl)-ph...)
Affinity DataIC50:  13.0nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184115(4'-trifluoromethyl-biphenyl-2-carboxylic acid {4-[...)
Affinity DataIC50:  13.3nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184134(CHEMBL263215 | N-[(S)-(ethyl-propyl-carbamoyl)-phe...)
Affinity DataIC50:  13.3nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184106(4'-trifluoromethyl-biphenyl-2-carboxylic acid [3-m...)
Affinity DataIC50:  14.8nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184117(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...)
Affinity DataIC50:  14.9nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184098(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-{[...)
Affinity DataIC50:  15.6nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184107(CHEMBL245300 | N-[(S)-(butyl-methyl-carbamoyl)-phe...)
Affinity DataIC50:  16.9nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184101(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-{[...)
Affinity DataIC50:  16.9nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184163(4'-trifluoromethyl-biphenyl-2-carboxylic acid [4-(...)
Affinity DataIC50:  17.3nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184162(CHEMBL379843 | N-((S)-2-oxo-1-phenyl-2-pyrrolidin-...)
Affinity DataIC50:  17.4nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184113(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...)
Affinity DataIC50:  18.3nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184126(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  20.5nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184154(CHEMBL206965 | N-((S)-benzylcarbamoyl-phenyl-methy...)
Affinity DataIC50:  22.5nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184146(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  23.1nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184119(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-piperid...)
Affinity DataIC50:  23.6nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184167(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...)
Affinity DataIC50:  26.6nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184103(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...)
Affinity DataIC50:  26.8nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184145(1-(4'-trifluoromethyl-biphenyl-2-carbonyl)-2,3-dih...)
Affinity DataIC50:  29nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184164(CHEMBL379475 | N-((S)-2-oxo-1-phenyl-2-piperidin-1...)
Affinity DataIC50:  29.5nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184168(CHEMBL378263 | N-[(S)-(cyclopropylmethyl-carbamoyl...)
Affinity DataIC50:  35.4nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184135(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)
Affinity DataIC50:  35.9nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184156(4'-trifluoromethyl-biphenyl-2-carboxylic acid {4-[...)
Affinity DataIC50:  55.8nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184157(4'-trifluoromethyl-biphenyl-2-carboxylic acid 4-[(...)
Affinity DataIC50:  61.1nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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