Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50017986
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189573(3-(4-iodo-phenyl)-5-methylene-7-aza-tricyclo[5.3.0...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189572(3-(4-bromo-phenyl)-5-methylene-7-aza-tricyclo[5.3....)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189574(3-(4-chloro-phenyl)-5-methylene-7-aza-tricyclo[5.3...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189571(CHEMBL383873 | [3-(4-bromo-phenyl)-7-aza-tricyclo[...)
Affinity DataKi:  2.94nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189572(3-(4-bromo-phenyl)-5-methylene-7-aza-tricyclo[5.3....)
Affinity DataKi:  2.94nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189569(CHEMBL215236 | [3-(4-chloro-phenyl)-7-aza-tricyclo...)
Affinity DataKi:  4.54nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189574(3-(4-chloro-phenyl)-5-methylene-7-aza-tricyclo[5.3...)
Affinity DataKi:  4.84nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189571(CHEMBL383873 | [3-(4-bromo-phenyl)-7-aza-tricyclo[...)
Affinity DataKi:  5.63nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189573(3-(4-iodo-phenyl)-5-methylene-7-aza-tricyclo[5.3.0...)
Affinity DataKi:  5.87nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataKi:  7.77nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189573(3-(4-iodo-phenyl)-5-methylene-7-aza-tricyclo[5.3.0...)
Affinity DataKi:  8.48nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189574(3-(4-chloro-phenyl)-5-methylene-7-aza-tricyclo[5.3...)
Affinity DataKi:  12.3nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189571(CHEMBL383873 | [3-(4-bromo-phenyl)-7-aza-tricyclo[...)
Affinity DataKi:  12.5nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189569(CHEMBL215236 | [3-(4-chloro-phenyl)-7-aza-tricyclo...)
Affinity DataKi:  13.0nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189568(CHEMBL216015 | [3-p-tolyl-7-aza-tricyclo[5.3.0.0*4...)
Affinity DataKi:  13.3nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataKi:  17.3nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189569(CHEMBL215236 | [3-(4-chloro-phenyl)-7-aza-tricyclo...)
Affinity DataKi:  18.8nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189568(CHEMBL216015 | [3-p-tolyl-7-aza-tricyclo[5.3.0.0*4...)
Affinity DataKi:  25.5nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataKi:  41.0nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189572(3-(4-bromo-phenyl)-5-methylene-7-aza-tricyclo[5.3....)
Affinity DataKi:  41.9nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189568(CHEMBL216015 | [3-p-tolyl-7-aza-tricyclo[5.3.0.0*4...)
Affinity DataKi:  98.3nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189570(5-methylene-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of (-)-[3H]NE uptake at NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed