Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50037765
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189360((1S,10S)-9-[(Isoquinoline-1-carbonyl)-amino]-6,10-...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191907(CHEMBL387453 | N-((R)-4-(2-((S)-2-hydroxy-5-oxo-te...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189360((1S,10S)-9-[(Isoquinoline-1-carbonyl)-amino]-6,10-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191905(CHEMBL425277 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50:  70nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191909(CHEMBL214226 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50:  80nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191902(CHEMBL214073 | isoquinoline-1-carboxylic acid {(R)...)
Affinity DataIC50:  130nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191906(CHEMBL215512 | N-((R)-4-(2-((S)-2-hydroxy-5-oxo-te...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191901(CHEMBL213978 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191908(CHEMBL441854 | benzo[b]thiophene-2-carboxylic acid...)
Affinity DataIC50:  320nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191904(CHEMBL384930 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50:  350nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189360((1S,10S)-9-[(Isoquinoline-1-carbonyl)-amino]-6,10-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191899(CHEMBL215385 | N-{(R)-4-[((S)-2-hydroxy-5-oxo-tetr...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191902(CHEMBL214073 | isoquinoline-1-carboxylic acid {(R)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191904(CHEMBL384930 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191905(CHEMBL425277 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191908(CHEMBL441854 | benzo[b]thiophene-2-carboxylic acid...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191907(CHEMBL387453 | N-((R)-4-(2-((S)-2-hydroxy-5-oxo-te...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191909(CHEMBL214226 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191901(CHEMBL213978 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191908(CHEMBL441854 | benzo[b]thiophene-2-carboxylic acid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191906(CHEMBL215512 | N-((R)-4-(2-((S)-2-hydroxy-5-oxo-te...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191906(CHEMBL215512 | N-((R)-4-(2-((S)-2-hydroxy-5-oxo-te...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191901(CHEMBL213978 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191902(CHEMBL214073 | isoquinoline-1-carboxylic acid {(R)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191905(CHEMBL425277 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191907(CHEMBL387453 | N-((R)-4-(2-((S)-2-hydroxy-5-oxo-te...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191899(CHEMBL215385 | N-{(R)-4-[((S)-2-hydroxy-5-oxo-tetr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191899(CHEMBL215385 | N-{(R)-4-[((S)-2-hydroxy-5-oxo-tetr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191904(CHEMBL384930 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191909(CHEMBL214226 | N-((R)-4-(2-((3S)-2-hydroxy-5-oxo-t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Caspase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed