Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 1540
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM19((2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3...)
Affinity DataKi:  500nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12008((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-6-(aminometh...)
Affinity DataKi:  500nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM11997((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-3-carbamimid...)
Affinity DataKi:  700nM ΔG°:  -34.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12005((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-4-amino-6-ca...)
Affinity DataKi:  700nM ΔG°:  -34.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12012((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5R,6R)-3-carbamimid...)
Affinity DataKi:  1.50E+3nM ΔG°:  -32.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12010((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-6-amino-4-ca...)
Affinity DataKi:  3.10E+3nM ΔG°:  -31.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM11998((1R,2S,3R,4R,5S)-5-amino-4-{[(2R,3R,4R,5S,6R)-3-am...)
Affinity DataKi:  5.00E+3nM ΔG°:  -30.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM11999((1S,2R,3R,4S,5R)-5-amino-2-{[(2R,3R,4R,5S,6R)-3-am...)
Affinity DataKi:  5.20E+3nM ΔG°:  -29.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12003((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-6-amino-4-ca...)
Affinity DataKi:  5.30E+3nM ΔG°:  -29.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12002((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-3-amino-6-(a...)
Affinity DataKi:  5.60E+3nM ΔG°:  -29.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12007((2R,3R,4R,5S,6R)-6-(carbamimidamidomethyl)-2-{[(1R...)
Affinity DataKi:  7.70E+3nM ΔG°:  -28.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12009((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-3-amino-6-(c...)
Affinity DataKi:  8.70E+3nM ΔG°:  -28.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12006((1S,2R,3R,4S,5R)-5-amino-2-{[(2R,3R,4R,5S,6R)-3-am...)
Affinity DataKi:  8.80E+3nM ΔG°:  -28.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12011((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-4-amino-6-ca...)
Affinity DataKi:  9.20E+3nM ΔG°:  -28.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12004((1R,2S,3R,4R,5S)-5-amino-4-{[(2R,3R,4R,5S,6R)-3-am...)
Affinity DataKi:  1.02E+4nM ΔG°:  -28.2kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12000((2R,3R,4R,5S,6R)-6-(aminomethyl)-2-{[(1R,2R,3S,4R,...)
Affinity DataKi:  1.09E+4nM ΔG°:  -28.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM12001(3-{[(2R,3S,4R,5R,6R)-5-amino-6-{[(1R,2R,3S,4R,6S)-...)
Affinity DataKi:  2.43E+4nM ΔG°:  -26.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Hawaii Biotech

LigandPNGBDBM8580((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...)
Affinity DataKi:  4.29E+4nM ΔG°:  -24.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed