Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50018452
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195947(CHEMBL374064 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195955(CHEMBL375533 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195948(CHEMBL220146 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195952(CHEMBL374251 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195946(CHEMBL223756 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195951(2-[3-(6-methoxypyridin-2-yl)-2-oxo-2,3-dihydro-1H-...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195945(2-[3-(1,1-dioxo-1-thiolan-3-yl)-2-oxo-2,3-dihydro-...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195943(CHEMBL220101 | N-((R)-3-methyl-2,5-dioxo-1',3'-dih...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195956((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195954(CHEMBL376292 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195950(2-[3-(3,5-difluorophenyl)-2-oxo-2,3-dihydro-1H-1,3...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195960((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)
Affinity DataKi:  43nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195961(CHEMBL219782 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195959(CHEMBL385322 | N-(2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataKi:  78nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195944(CHEMBL219721 | N-{2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataKi:  87nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195958(CHEMBL221160 | N-(3-methyl-2,5-dioxo-1',3'-dihydro...)
Affinity DataKi:  103nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195942(CHEMBL223805 | N-(2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataKi:  280nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195949(CHEMBL220336 | N-(2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataKi:  309nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195957(CHEMBL376263 | N-(2,5-dioxo-3',4'-dihydro-1'H-spir...)
Affinity DataKi:  607nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195953(CHEMBL222198 | N-[(4S)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataKi:  1.05E+3nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195955(CHEMBL375533 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataIC50:  24nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195947(CHEMBL374064 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataIC50:  39nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195948(CHEMBL220146 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195952(CHEMBL374251 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195951(2-[3-(6-methoxypyridin-2-yl)-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50:  54nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195943(CHEMBL220101 | N-((R)-3-methyl-2,5-dioxo-1',3'-dih...)
Affinity DataIC50:  61nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195945(2-[3-(1,1-dioxo-1-thiolan-3-yl)-2-oxo-2,3-dihydro-...)
Affinity DataIC50:  64nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195946(CHEMBL223756 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataIC50:  64nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195956((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)
Affinity DataIC50:  78nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195954(CHEMBL376292 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195960((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)
Affinity DataIC50:  120nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195950(2-[3-(3,5-difluorophenyl)-2-oxo-2,3-dihydro-1H-1,3...)
Affinity DataIC50:  180nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195961(CHEMBL219782 | N-[(4R)-3-methyl-2,5-dioxo-1',3'-di...)
Affinity DataIC50:  350nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195944(CHEMBL219721 | N-{2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataIC50:  430nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195959(CHEMBL385322 | N-(2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataIC50:  530nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195942(CHEMBL223805 | N-(2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataIC50:  690nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195958(CHEMBL221160 | N-(3-methyl-2,5-dioxo-1',3'-dihydro...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195949(CHEMBL220336 | N-(2,5-dioxo-1',3'-dihydrospiro[imi...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195957(CHEMBL376263 | N-(2,5-dioxo-3',4'-dihydro-1'H-spir...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195956((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195956((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195956((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed