Compile Data Set for Download or QSAR
maximum 50k data
Found 106 Enz. Inhib. hit(s) with all data for entry = 50018676
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198035(CHEMBL227501 | [(R)-2-methyl-1-(3'-methyl-biphenyl...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198034(CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198030(CHEMBL228188 | [(R)-1-(3'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM12072((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM12072((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198031(CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198031(CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198040(CHEMBL389898 | [(R)-2-methyl-1-(4'-pyrrolidin-1-yl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198037(CHEMBL228187 | [(R)-1-(3'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM12072((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198031(CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198040(CHEMBL389898 | [(R)-2-methyl-1-(4'-pyrrolidin-1-yl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198034(CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM12072((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198034(CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084301((S)-2-(4'-fluoro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084293((S)-2-(4'-chloro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198038(CHEMBL227824 | [(R)-1-(4'-ethoxy-biphenyl-4-sulfon...)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  13nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198035(CHEMBL227501 | [(R)-2-methyl-1-(3'-methyl-biphenyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198034(CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198035(CHEMBL227501 | [(R)-2-methyl-1-(3'-methyl-biphenyl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198030(CHEMBL228188 | [(R)-1-(3'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  24nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198031(CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198035(CHEMBL227501 | [(R)-2-methyl-1-(3'-methyl-biphenyl...)
Affinity DataIC50:  26nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198034(CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  28nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198030(CHEMBL228188 | [(R)-1-(3'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198039(CHEMBL374377 | [(R)-1-(4'-fluoro-biphenyl-4-sulfon...)
Affinity DataIC50:  32nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198031(CHEMBL227598 | [(R)-1-(4'-isopropoxy-biphenyl-4-su...)
Affinity DataIC50:  36nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084301((S)-2-(4'-fluoro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50084301((S)-2-(4'-fluoro-biphenyl-4-sulfonylamino)-3-methy...)
Affinity DataIC50:  43nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  45nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198033(CHEMBL227484 | [(R)-2-methyl-1-(4'-methyl-biphenyl...)
Affinity DataIC50:  45nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50198034(CHEMBL376557 | [(R)-1-(4'-chloro-biphenyl-4-sulfon...)
Affinity DataIC50:  47nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 106 total ) | Next | Last >>
Jump to: