Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50019136
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202186((Z)-5-((5-(4-chlorobenzylthio)-1-methyl-3-(trifluo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202187(5-((5-(4-(4-chlorophenyl)piperazin-1-yl)-1-phenyl-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202196(5-((5-(4-tert-butylbenzylthio)-1-methyl-3-(trifluo...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202181(5-((5-(4-chlorobenzylthio)-1-phenyl-3-(trifluorome...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202190(5-((1,3-diphenyl-5-(thiophen-2-ylmethylthio)-1H-py...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202200(5-((5-(4-chlorophenethoxy)-1-phenyl-3-(trifluorome...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202194(5-((5-(4-chlorobenzylthio)-1-cyclohexyl-3-(trifluo...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202189(5-((1-cyclohexyl-5-(furan-2-ylmethylthio)-3-phenyl...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202192(5-((5-(4-methylpiperazin-1-yl)-1,3-diphenyl-1H-pyr...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202184(5-((5-(4-chlorobenzylthio)-1-phenyl-3-(trifluorome...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202199(5-((5-(furan-2-ylmethylthio)-1,3-diphenyl-1H-pyraz...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202185(5-((5-(4-fluorophenethoxy)-1-phenyl-3-(trifluorome...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202196(5-((5-(4-tert-butylbenzylthio)-1-methyl-3-(trifluo...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of ADAMTS4 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202188(5-((1-cyclohexyl-3-phenyl-5-(4-(pyrimidin-2-yl)pip...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202193(5-((1-methyl-3-phenyl-5-(p-tolylthio)-1H-pyrazol-4...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202191(5-((5-(4-(4-chlorophenyl)piperazin-1-yl)-1-methyl-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202183(5-((1-phenyl-5-(2-(thiophen-2-yl)ethoxy)-3-(triflu...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202198(5-((1-cyclohexyl-5-(4-(pyrimidin-2-yl)piperazin-1-...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202197(5-((5-(furan-2-ylmethylthio)-1-methyl-3-phenyl-1H-...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202195(5-((5-(benzylthio)-1-phenyl-3-(trifluoromethyl)-1H...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202182(5-((5-(2-chlorobenzylthio)-1-methyl-3-(trifluorome...)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibition of ADAMTS5 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50202186((Z)-5-((5-(4-chlorobenzylthio)-1-methyl-3-(trifluo...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of ADAMTS4 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed