Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50019457
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204834(2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pterid...)
Affinity DataIC50:  53nMAssay Description:Inhibition of TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  123nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50204832(4-(2-(5-bromo-2-fluorophenyl)pteridin-4-ylamino)-N...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed