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Found 17 Enz. Inhib. hit(s) with all data for entry = 2534
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21710(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  9.00E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)
Affinity DataEC50:  1.20E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21712(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  3.00E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21713(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  3.10E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21714(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  2.10E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21715(3-[benzyl(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  2.50E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21716(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  840nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21717(3-[(E)-2-(4-{[5-tert-butyl-3-(2,6-dichlorophenyl)-...)
Affinity DataEC50:  1.30E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21718(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-ph...)
Affinity DataEC50:  1.58E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21719(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(n...)
Affinity DataEC50:  2.22E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21720(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(4...)
Affinity DataEC50:  3.39E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21721(3-[(4-{[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-ox...)
Affinity DataEC50:  1.30E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21722(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(naphtha...)
Affinity DataEC50:  4.00E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21723(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(4-pheny...)
Affinity DataEC50:  3.70E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21674((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...)
Affinity DataEC50:  2.70E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1...)
Affinity DataEC50:  70nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21711(Isoxazole derivative, 11b | N,N-dibenzyl-3-[(E)-2-...)
Affinity DataEC50:  3.51E+4nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed