Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50020085
TargetProthrombin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataKi:  2nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataKi:  4nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataKi:  17nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataKi:  154nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataKi:  367nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206984((2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METH...)
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataIC50: >1.58E+5nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed