Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50020283
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of chemotaxis in human MCP1 monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  2.04nMAssay Description:Inhibition of Ca2+ flux in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212146(1-ethyl-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212122((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212146(1-ethyl-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212140((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212134(CHEMBL231038 | N-{[3-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212131(1-(cyclopropylmethyl)-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  5.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212135(CHEMBL266017 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  6.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212145((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  7.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212139((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212125(CHEMBL389610 | N-{[3-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50:  8.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212141((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  9nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212126(CHEMBL388007 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212130((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212131(1-(cyclopropylmethyl)-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212145((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212144(CHEMBL230831 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  15.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212138((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212134(CHEMBL231038 | N-{[3-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212122((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212126(CHEMBL388007 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  17.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212124((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212132((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212142(CHEMBL230078 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212139((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212123(CHEMBL231143 | N-{[3-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50:  27nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212137((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212129(1-(cyclobutylmethyl)-N-{[3-fluoro-5-(trifluorometh...)
Affinity DataIC50:  32nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212138((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  44.3nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212135(CHEMBL266017 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  45nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212140((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  57nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212142(CHEMBL230078 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  63.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212124((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  64nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212130((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  65.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212143((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  67nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212125(CHEMBL389610 | N-{[3-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50:  74nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212144(CHEMBL230831 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  93nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212141((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  126nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212123(CHEMBL231143 | N-{[3-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50:  128nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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