Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50020498
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM19489((2S)-N-(cyanomethyl)-4-methyl-2-[[(1S)-2,2,2-trifl...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214543((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214542((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214540((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214546((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  10nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214539((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  13nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214545((S)-4-methylsulfanyl-2-{(S)-4-methyl-2-[(S)-2,2,2-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214551((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  41nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214553((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  66nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214556((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  67nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214554((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  87nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214548((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  109nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214549((S)-4-methylsulfanyl-2-{(S)-4-methyl-2-[(S)-2,2,2-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214547((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  151nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214555((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  174nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  238nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214544((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  238nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214552((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  273nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214538((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  277nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214541((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214550((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  6.07E+3nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214546((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  4.11E+4nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214539((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  5.57E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214546((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  6.67E+4nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214539((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50:  7.69E+4nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214546((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214539((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214537((S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanes...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed