Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 2393
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19968((2R,6S,7R)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)
Affinity DataKi:  0.190nM ΔG°:  -54.9kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19985((2R,4S,6S,7R)-7-(4-hydroxyphenyl)-4-methyl-8-oxatr...)
Affinity DataKi:  0.310nM ΔG°:  -53.7kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19983((2R,4R,6S,7R)-7-(4-hydroxyphenyl)-4-(trifluorometh...)
Affinity DataKi:  0.410nM ΔG°:  -53.0kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19982((2R,6S,7R)-4,4-difluoro-7-(4-hydroxyphenyl)-8-oxat...)
Affinity DataKi:  0.440nM ΔG°:  -52.9kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19984((2R,4S,6S,7R)-7-(4-hydroxyphenyl)-4-(trifluorometh...)
Affinity DataKi:  0.700nM ΔG°:  -51.7kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19968((2R,6S,7R)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)
Affinity DataKi:  2.70nM ΔG°:  -48.4kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19985((2R,4S,6S,7R)-7-(4-hydroxyphenyl)-4-methyl-8-oxatr...)
Affinity DataKi:  3.30nM ΔG°:  -47.9kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19979((2R,6S,7R)-12-hydroxy-7-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi:  6.92nM ΔG°:  -46.1kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19983((2R,4R,6S,7R)-7-(4-hydroxyphenyl)-4-(trifluorometh...)
Affinity DataKi:  7.20nM ΔG°:  -46.0kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19982((2R,6S,7R)-4,4-difluoro-7-(4-hydroxyphenyl)-8-oxat...)
Affinity DataKi:  8.30nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19981((1S,9S,10R)-4-hydroxy-9-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi:  10.2nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19984((2R,4S,6S,7R)-7-(4-hydroxyphenyl)-4-(trifluorometh...)
Affinity DataKi:  12.4nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19980((1S,9S,10R)-4-hydroxy-9-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi:  375nM ΔG°:  -36.3kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19981((1S,9S,10R)-4-hydroxy-9-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi:  410nM ΔG°:  -36.1kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19979((2R,6S,7R)-12-hydroxy-7-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi:  700nM ΔG°:  -34.8kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19980((1S,9S,10R)-4-hydroxy-9-(4-hydroxyphenyl)-8-oxatri...)
Affinity DataKi: >1.00E+3nM ΔG°: >-33.9kJ/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed