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Found 27 Enz. Inhib. hit(s) with all data for entry = 50020906
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218834(2-(6-chloro-5-(3-(2,4-difluorophenyl)-5,6,7,8-tetr...)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218821(1-(5-(3-(2,4-difluorophenyl)-5,6,7,8-tetrahydroimi...)
Affinity DataIC50:  13nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218824(2-(5-(3-(2,4-difluorophenyl)-5,6,7,8-tetrahydroimi...)
Affinity DataIC50:  13nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218820(2-(6-chloro-5-(3-(2,4-difluorophenyl)-5,6,7,8-tetr...)
Affinity DataIC50:  14nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218829(1-(5-(3-(2,4-difluorophenyl)-5,6,7,8-tetrahydroimi...)
Affinity DataIC50:  16nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218839((6-chloro-1-methyl-1H-indol-5-yl)(1-(2-chloropheny...)
Affinity DataIC50:  26nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218826(2-(5-(3-(2,4-difluorophenyl)-5,6,7,8-tetrahydroimi...)
Affinity DataIC50:  29nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218818(2-(5-(1-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-pyr...)
Affinity DataIC50:  29nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218835((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  30nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218828(2-(6-chloro-5-(1-(2-chlorophenyl)-4,5,6,7-tetrahyd...)
Affinity DataIC50:  33nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218840((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  37nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218823(2-(5-(1-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-pyr...)
Affinity DataIC50:  37nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218817((3-(2,4-difluorophenyl)-5,6-dihydroimidazo[1,5-a]p...)
Affinity DataIC50:  38nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218833((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  39nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218827((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  40nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218838((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  40nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218825((6-chloro-1-methyl-1H-indol-5-yl)(3-(2,4-difluorop...)
Affinity DataIC50:  50nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218822((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  55nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218836((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  68nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218841((1-(2-chloro-4-fluorophenyl)-6,7-dihydro-1H-pyrazo...)
Affinity DataIC50:  97nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218830((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  112nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218837((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  137nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218816((1-(2-chlorophenyl)-6,7-dihydro-1H-pyrazolo[4,3-c]...)
Affinity DataIC50:  154nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218831((3-(2,4-difluorophenyl)-5,6-dihydroimidazo[1,5-a]p...)
Affinity DataIC50:  164nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218819((2,6-difluorophenyl)(3-(2,4-difluorophenyl)-5,6-di...)
Affinity DataIC50:  167nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218815(2-(6-chloro-5-(4-(2,4-difluorophenyl)-5,6,7,8-tetr...)
Affinity DataIC50:  195nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218832((2,4-difluorophenyl)(3-(2,4-difluorophenyl)-5,6-di...)
Affinity DataIC50:  593nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed