Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50021117
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182092(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50152989(3-(5-carbamoyl-3-(4-iodophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162828(1-(1-(3-(3-(3,4-dichlorophenyl)-5-(methylsulfonyl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221229(3-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221228(1-(4-(1H-pyrrolo[3,2-c]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221221(CHEMBL397622 | ethyl 3-(1-(2-hydroxy-3-(5-(methyls...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221219(1-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221241(1-(4-(6-chloro-1H-indol-3-yl)piperidin-1-yl)-3-(5-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221238(1-(4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl)-3-(5...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221230(1-(4-(1H-pyrrolo[2,3-c]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221225(1-(4-(7-chloro-1H-indol-3-yl)piperidin-1-yl)-3-(5-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221223(1-(4-(5-chloro-2-methyl-1H-indol-3-yl)piperidin-1-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221227(CHEMBL396600 | N-ethyl-6-fluoro-3-(1-(3-(5-(methyl...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221230(1-(4-(1H-pyrrolo[2,3-c]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  38nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221214(6-fluoro-3-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluo...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221240(1-(4-(5-chloro-1H-indol-3-yl)piperidin-1-yl)-3-(5-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221233(CHEMBL395039 | N-(2-aminoethyl)-6-fluoro-3-(1-(3-(...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221222(1-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,6,7-te...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221228(1-(4-(1H-pyrrolo[3,2-c]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221218(1-(4-(5-methyl-1H-indol-3-yl)piperidin-1-yl)-3-(5-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221236(1-(1-(3-(4-(1H-indol-3-yl)piperidin-1-yl)-2-hydrox...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221220(1-(4-(1H-pyrrolo[3,2-c]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221217(1-(1-(3-(4-(5-chloro-1H-indol-3-yl)piperidin-1-yl)...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221216(1-(4-(1H-pyrrolo[3,2-b]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  95nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221226(6-fluoro-3-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluo...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221216(1-(4-(1H-pyrrolo[3,2-b]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221242(CHEMBL238408 | methyl 6-fluoro-3-(1-(2-hydroxy-3-(...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221231(CHEMBL238410 | methyl 6-fluoro-3-(1-(3-(5-(methyls...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221237(CHEMBL238407 | methyl 3-(1-(3-(5-acetyl-3-(4-(trif...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221220(1-(4-(1H-pyrrolo[3,2-c]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  150nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221234(1-(4-(6-fluorobenzo[b]thiophen-3-yl)piperidin-1-yl...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221213(1-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  195nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221215(1-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221239(CHEMBL394422 | methyl 3-(1-(3-(5-acetyl-3-(4-(trif...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221215(1-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-...)
Affinity DataIC50:  240nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221224(1-(1-(3-(4-(6-fluorobenzo[b]thiophen-3-yl)piperidi...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221214(6-fluoro-3-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluo...)
Affinity DataIC50:  340nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221232(1-(1-(3-(4-(6-fluorobenzofuran-3-yl)piperidin-1-yl...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221235(6-fluoro-N,N-dimethyl-3-(1-(3-(5-(methylsulfonyl)-...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221221(CHEMBL397622 | ethyl 3-(1-(2-hydroxy-3-(5-(methyls...)
Affinity DataIC50:  410nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50182092(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Affinity DataIC50:  800nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50162828(1-(1-(3-(3-(3,4-dichlorophenyl)-5-(methylsulfonyl)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50152989(3-(5-carbamoyl-3-(4-iodophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50:  800nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221219(1-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidin-1-yl...)
Affinity DataIC50:  860nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221227(CHEMBL396600 | N-ethyl-6-fluoro-3-(1-(3-(5-(methyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221231(CHEMBL238410 | methyl 6-fluoro-3-(1-(3-(5-(methyls...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221233(CHEMBL395039 | N-(2-aminoethyl)-6-fluoro-3-(1-(3-(...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221226(6-fluoro-3-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed