Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50022073
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231424((S)-3-(4-(4-(2,6-dicyanophenyl)piperazin-1-yl)phen...)
Affinity DataIC50:  19nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231422((S)-2-((R)-1-(3,5-dichlorophenylsulfonyl)pyrrolidi...)
Affinity DataIC50:  28nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231417((S)-4-((1-carboxy-2-(4-(4-phenylpiperazin-1-yl)phe...)
Affinity DataIC50:  42nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231430((S)-3-(4-(4-(5-acetylthiophen-2-yl)piperazin-1-yl)...)
Affinity DataIC50:  67nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231413((S)-3-(4-(4-(2-cyanophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50:  67nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231419((S)-3-(4-(4-(2-nitrophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50:  69nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231412((S)-3-(4-(4-(pyrazin-2-yl)piperazin-1-yl)phenyl)-2...)
Affinity DataIC50:  75nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231423((S)-3-(4-(4-phenylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50:  76nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231429((S)-3-(4-(4-(cyclopropanecarbonyl)piperazin-1-yl)p...)
Affinity DataIC50:  80nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231408((S)-3-(4-(4-(2-cyanophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50:  99nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231421((S)-3-(4-(4-(4-cyanophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50:  101nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231431((S)-3-(4-(4-phenylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50:  123nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231436((S)-2-((S)-1-(phenylsulfonyl)pyrrolidine-2-carboxa...)
Affinity DataIC50:  124nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231433((S)-3-(4-(4-(3-ethoxy-3-oxopropyl)piperazin-1-yl)p...)
Affinity DataIC50:  130nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231434((S)-3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)phenyl...)
Affinity DataIC50:  135nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231420((S)-3-(4-(4-(4-nitrophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50:  143nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231409((S)-3-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl...)
Affinity DataIC50:  152nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231414((S)-3-(4-(4-(3-methoxyphenyl)piperazin-1-yl)phenyl...)
Affinity DataIC50:  170nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231425((S)-3-(4-(4-(pyridin-2-yl)piperazin-1-yl)phenyl)-2...)
Affinity DataIC50:  179nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231432((S)-3-(4-(4-phenylpiperazin-1-yl)phenyl)-2-((S)-3-...)
Affinity DataIC50:  196nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231415((S)-3-(4-(4-(ethylcarbamoyl)piperazin-1-yl)phenyl)...)
Affinity DataIC50:  200nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231435((S)-3-(4-(4-benzylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50:  222nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231411((S)-3-(4-(4-methylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50:  235nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231410((S)-3-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)phenyl)...)
Affinity DataIC50:  239nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231406((S)-3-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)phe...)
Affinity DataIC50:  327nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231418((S)-3-(4-(4-p-tolylpiperazin-1-yl)phenyl)-2-((S)-1...)
Affinity DataIC50:  353nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231428((S)-3-[4-(4-biphenyl-4-yl-piperazin-1-yl)-phenyl]-...)
Affinity DataIC50:  450nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231407((S)-2-(3,5-dichloroisonicotinamido)-3-(4-(4-phenyl...)
Affinity DataIC50:  510nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231416((S)-2-(2,6-dichlorobenzamido)-3-(4-(4-phenylpipera...)
Affinity DataIC50:  1.12E+3nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231426((S)-2-(2-fluoro-6-(trifluoromethyl)benzamido)-3-(4...)
Affinity DataIC50:  4.32E+3nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50231427((S)-2-(2,6-difluorobenzamido)-3-(4-(4-phenylpipera...)
Affinity DataIC50:  6.81E+3nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed