Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50026582
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(CHEMBL473866 | N-[5-(9H-Carbazol-4-yloxy)pentyl]-N...)
Affinity DataIC50:  1.54nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(CHEMBL478667 | N-[4-(9H-Carbazol-4-yloxy)butyl]-N'...)
Affinity DataIC50:  1.65nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263213(CHEMBL478666 | N-[3-(9H-Carbazol-4-yloxy)propyl]-N...)
Affinity DataIC50:  2.15nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263262(CHEMBL474268 | N-[6-(9H-Carbazol-4-yloxy)hexyl]-N'...)
Affinity DataIC50:  2.57nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10514(CHEMBL191758 | N-(3-aminopropyl)-6-chloro-1,2,3,4-...)
Affinity DataIC50:  21.5nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  45.8nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263262(CHEMBL474268 | N-[6-(9H-Carbazol-4-yloxy)hexyl]-N'...)
Affinity DataIC50:  137nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(CHEMBL473866 | N-[5-(9H-Carbazol-4-yloxy)pentyl]-N...)
Affinity DataIC50:  189nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(CHEMBL478667 | N-[4-(9H-Carbazol-4-yloxy)butyl]-N'...)
Affinity DataIC50:  211nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263213(CHEMBL478666 | N-[3-(9H-Carbazol-4-yloxy)propyl]-N...)
Affinity DataIC50:  296nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  424nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263213(CHEMBL478666 | N-[3-(9H-Carbazol-4-yloxy)propyl]-N...)
Affinity DataIC50:  740nMAssay Description:Inhibition of NMDA NR1/NR2B receptor (unknown origin) expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10514(CHEMBL191758 | N-(3-aminopropyl)-6-chloro-1,2,3,4-...)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50062599(3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...)
Affinity DataIC50:  9.52E+3nMAssay Description:Inhibition of NMDA NR1/NR2B receptor (unknown origin) expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current respons...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263262(CHEMBL474268 | N-[6-(9H-Carbazol-4-yloxy)hexyl]-N'...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor (unknown origin) expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263215(CHEMBL473866 | N-[5-(9H-Carbazol-4-yloxy)pentyl]-N...)
Affinity DataIC50:  1.82E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor (unknown origin) expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50263214(CHEMBL478667 | N-[4-(9H-Carbazol-4-yloxy)butyl]-N'...)
Affinity DataIC50:  3.03E+4nMAssay Description:Inhibition of NMDA NR1/NR2B receptor (unknown origin) expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current respons...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed