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Found 11 Enz. Inhib. hit(s) with all data for entry = 50026642
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM22826(2,3-dioxo-2,3-dihydro-1H-indole-7-carboxylic acid ...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human recombinant DNA ligase 1 using nicked DNA substrate by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262041(5-(((5-carboxy-2-methylfuran-3-yl)methylthio)methy...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262039(3-amino-2-(benzylideneamino)-5-mercaptophenol | CH...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM22826(2,3-dioxo-2,3-dihydro-1H-indole-7-carboxylic acid ...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50261995(CHEMBL467192 | N'-(2-hydroxy-5-nitrobenzylidene)-2...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262038(3-(4-Bromo-benzenesulfonyl)-N-[2-(4-sulfamoyl-phen...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50261993(5-(methylthio)thiophene-2-carboxylic acid | CHEMBL...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262037(5-(2-(4-hydroxy-3-nitrobenzylidene)hydrazinyl)-4-c...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50261994(2-(7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-ylth...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262040(7-(4-methoxyphenyl)pteridine-2,4-diol | CHEMBL5112...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA ligase 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262042((2-hydroxyphenyl)(4-hydroxyphenyl)methanone | CHEM...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed