Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50026885
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(CHEMBL486840 | N-(4-Chlorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245034(CHEMBL488018 | N-(3,4-Difluorophenyl)-6,7-dimethox...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245069(CHEMBL487835 | N-(4-Fluorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245071(3-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245072(4-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50:  61nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245034(CHEMBL488018 | N-(3,4-Difluorophenyl)-6,7-dimethox...)
Affinity DataIC50:  69nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(CHEMBL487635 | N-Cycloheptyl-6,7-dimethoxy-2-(4-py...)
Affinity DataIC50:  70nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245112(CHEMBL488690 | N-(4-Chlorophenyl)-2-{4-[2-(diethyl...)
Affinity DataIC50:  92nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245070(2-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50:  98nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(CHEMBL486840 | N-(4-Chlorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(CHEMBL487635 | N-Cycloheptyl-6,7-dimethoxy-2-(4-py...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245114(CHEMBL488855 | N-(4-Chlorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(CHEMBL486840 | N-(4-Chlorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245036(CHEMBL486840 | N-(4-Chlorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  150nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245113(CHEMBL488691 | N-(4-Chlorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(CHEMBL487635 | N-Cycloheptyl-6,7-dimethoxy-2-(4-py...)
Affinity DataIC50:  200nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50244380(CHEMBL487635 | N-Cycloheptyl-6,7-dimethoxy-2-(4-py...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245035(CHEMBL488704 | N-(3-Bromophenyl)-6,7-dimethoxy-2-(...)
Affinity DataIC50:  220nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245071(3-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50:  280nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245069(CHEMBL487835 | N-(4-Fluorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  320nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245072(4-[(1-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquin...)
Affinity DataIC50:  360nMAssay Description:Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245035(CHEMBL488704 | N-(3-Bromophenyl)-6,7-dimethoxy-2-(...)
Affinity DataIC50:  510nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245111(CHEMBL487665 | N-(4-Chlorophenyl)-2-(4-cyclohexyl-...)
Affinity DataIC50:  550nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245069(CHEMBL487835 | N-(4-Fluorophenyl)-6,7-dimethoxy-2-...)
Affinity DataIC50:  710nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245034(CHEMBL488018 | N-(3,4-Difluorophenyl)-6,7-dimethox...)
Affinity DataIC50:  820nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed