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Found 14 Enz. Inhib. hit(s) with all data for entry = 50026922
TargetCathepsin K(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223929(7-(2,2-Dimethyl-propyl)-6-(3-methyl-2,4-dioxo-1,3,...)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223934(7-(2,2-Dimethyl-propyl)-6-(2,4-dioxo-8-propyl-1,3,...)
Affinity DataIC50:  27nMAssay Description:Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223913(6-((1,3-dioxo-2,8-diazaspiro[4.5]decan-2-yl)methyl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244510(7-(2,2-dimethylpropyl)-6-[(5-methoxy-2-oxospiro[in...)
Affinity DataIC50:  44nMAssay Description:Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244460(7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-1,3,8-triazas...)
Affinity DataIC50:  76nMAssay Description:Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223919(7-(2,2-dimethylpropyl)-6-[(5-fluoro-2-oxospiro[ind...)
Affinity DataIC50:  78nMAssay Description:Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50245103(7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-3-propyl-1,3,...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50245103(7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-3-propyl-1,3,...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244459(7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-1,3,8-triazas...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244460(7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-1,3,8-triazas...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244510(7-(2,2-dimethylpropyl)-6-[(5-methoxy-2-oxospiro[in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244460(7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-1,3,8-triazas...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244510(7-(2,2-dimethylpropyl)-6-[(5-methoxy-2-oxospiro[in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50244459(7-(2,2-dimethylpropyl)-6-[(2,4-dioxo-1,3,8-triazas...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed