Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50000750
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009407(But-3-enoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009411(6-{2-[8-(4-Fluoro-benzyloxy)-2,6-dimethyl-1,2,6,7,...)
Affinity DataIC50:  4.70nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009413(CHEMBL3085466 | Phenyl-acetic acid 8-[2-(4-hydroxy...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009414(6-[2-(8-Benzyloxy-2,6-dimethyl-1,2,6,7,8,8a-hexahy...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009409(6-{2-[8-(4-Chloro-benzyloxy)-2,6-dimethyl-1,2,6,7,...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009408(Acetic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran...)
Affinity DataIC50:  269nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009415(6-{2-[2,6-Dimethyl-8-(2-methyl-allyloxy)-1,2,6,7,8...)
Affinity DataIC50:  360nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009410(6-[2-(8-Allyloxy-2,6-dimethyl-1,2,6,7,8,8a-hexahyd...)
Affinity DataIC50:  370nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009412(4-Hydroxy-6-[2-(8-methoxy-2,6-dimethyl-1,2,6,7,8,8...)
Affinity DataIC50:  2.81E+3nMAssay Description:In vitro inhibitory activity of the compound against rat liver HMG-CoA reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed