Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 2869
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25558(4-arylamino-3-pyridinecarbonitrile, 4p | 5-(3,4-di...)
Affinity DataKi:  79nM ΔG°:  -40.1kJ/mole IC50:  70nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25543(4-[(3-bromophenyl)amino]-5-(3,4-dimethoxyphenyl)py...)
Affinity DataKi:  4.90E+3nM ΔG°:  -30.0kJ/mole IC50:  4.60E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25553(4-[(2,4-dichlorophenyl)amino]-5-(3,4-dimethoxyphen...)
Affinity DataIC50:  80nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25554(4-arylamino-3-pyridinecarbonitrile, 4l | 5-(3,4-di...)
Affinity DataIC50:  160nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25551(4-arylamino-3-pyridinecarbonitrile, 4i | 5-(3,4-di...)
Affinity DataIC50:  400nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25555(4-[(2,5-dichlorophenyl)amino]-5-(3,4-dimethoxyphen...)
Affinity DataIC50:  470nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25550(4-arylamino-3-pyridinecarbonitrile, 4h | 5-(3,4-di...)
Affinity DataIC50:  900nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25546(4-arylamino-3-pyridinecarbonitrile, 4d | 5-(3,4-di...)
Affinity DataIC50:  1.40E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25544(4-arylamino-3-pyridinecarbonitrile, 4b | 5-(3,4-di...)
Affinity DataIC50:  1.60E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25560(4-(2,3-dihydro-1H-inden-5-ylamino)-5-(3,4-dimethox...)
Affinity DataIC50:  2.00E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25559(4-arylamino-3-pyridinecarbonitrile, 4q | 5-(3,4-di...)
Affinity DataIC50:  2.20E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25557(4-arylamino-3-pyridinecarbonitrile, 4o | 5-(3,4-di...)
Affinity DataIC50:  2.20E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25556(4-[(3,4-dichlorophenyl)amino]-5-(3,4-dimethoxyphen...)
Affinity DataIC50:  2.40E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25549(4-[(4-chlorophenyl)amino]-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50:  2.80E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25545(4-[(3-chlorophenyl)amino]-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50:  3.90E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25552(4-arylamino-3-pyridinecarbonitrile, 4j | 5-(3,4-di...)
Affinity DataIC50:  8.40E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25547(4-arylamino-3-pyridinecarbonitrile, 4e | 5-(3,4-di...)
Affinity DataIC50: >3.00E+4nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25548(4-arylamino-3-pyridinecarbonitrile, 4f | 4-{[3-(be...)
Affinity DataIC50: >3.00E+4nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed