Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 2937
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University Of Milano

LigandPNGBDBM26205((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(2-ami...)
Affinity DataKi:  220nM ΔG°:  -37.6kJ/mole IC50:  250nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University Of Milano

LigandPNGBDBM26203((3S,6S,7S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphe...)
Affinity DataKi:  250nM ΔG°:  -37.3kJ/mole IC50:  270nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University Of Milano

LigandPNGBDBM13211((3S,6S,9aS)-6-[(2S)-2-aminobutanamido]-N-(diphenyl...)
Affinity DataKi:  420nM ΔG°:  -36.0kJ/mole IC50:  460nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
University Of Milano

LigandPNGBDBM26204((3S,6S,7R,9aS)-6-[(2S)-2-aminobutanamido]-7-(amino...)
Affinity DataKi:  870nM ΔG°:  -34.2kJ/mole IC50:  970nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair