Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50038775
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275719(1,4-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)quino...)
Affinity DataIC50:  1.41nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50157597(6-[ethyl-(2-methoxy-benzyl)-amino]-1-(1'-{6-[ethyl...)
Affinity DataIC50:  3.32nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275716(1,1'-(benzo[lmn][3,8]phenanthroline-2,7(1H,3H,6H,8...)
Affinity DataIC50:  4.83nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275722(2,6-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pyr...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275721(2,2'-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275718(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50:  15.9nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50124570(6-[Ethyl-(2-methoxy-benzyl)-amino]-hexanoic acid [...)
Affinity DataIC50:  16.1nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  23.1nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275712(6-[Ethyl-(2-methoxybenzyl)amino]-1-(4-{6-[ethyl-(2...)
Affinity DataIC50:  25.7nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275724(2-{6-[Ethyl-(2-methoxybenzyl)amino]hexyl}benzo[de]...)
Affinity DataIC50:  53.5nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275717(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50:  68.9nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275720(1,3-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}imi...)
Affinity DataIC50:  72.4nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275719(1,4-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)quino...)
Affinity DataIC50:  95.8nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(6-[(2-Methoxy-benzyl)-methyl-amino]-hexanoic acid ...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275721(2,2'-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[...)
Affinity DataIC50:  293nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275724(2-{6-[Ethyl-(2-methoxybenzyl)amino]hexyl}benzo[de]...)
Affinity DataIC50:  416nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275720(1,3-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}imi...)
Affinity DataIC50:  876nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275716(1,1'-(benzo[lmn][3,8]phenanthroline-2,7(1H,3H,6H,8...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275718(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50124570(6-[Ethyl-(2-methoxy-benzyl)-amino]-hexanoic acid [...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275722(2,6-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pyr...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275713(CHEMBL499825 | cis-6-[Ethyl-(2-methoxybenzyl)amino...)
Affinity DataIC50:  4.16E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275714((+/-)-trans-6-[Ethyl-(2-methoxybenzyl)amino]hexano...)
Affinity DataIC50:  5.47E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  7.42E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  8.13E+3nMAssay Description:Inhibition of human recombinant AChE-induced amyloid beta (1-40) aggregation by thioflavin T formation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50157597(6-[ethyl-(2-methoxy-benzyl)-amino]-1-(1'-{6-[ethyl...)
Affinity DataIC50:  8.49E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275715(CHEMBL499722 | trans-6-[Ethyl-(2-methoxybenzyl)ami...)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  9.69E+3nMAssay Description:Inhibition of self-induced amyloid beta (1-40) aggregation by thioflavin T formation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275717(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275712(6-[Ethyl-(2-methoxybenzyl)amino]-1-(4-{6-[ethyl-(2...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(6-[(2-Methoxy-benzyl)-methyl-amino]-hexanoic acid ...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM31904(CHEMBL345124 | Propidium | Propidium Iodide, 2 | p...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275715(CHEMBL499722 | trans-6-[Ethyl-(2-methoxybenzyl)ami...)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275713(CHEMBL499825 | cis-6-[Ethyl-(2-methoxybenzyl)amino...)
Affinity DataIC50:  3.08E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM31904(CHEMBL345124 | Propidium | Propidium Iodide, 2 | p...)
Affinity DataIC50:  3.23E+4nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275714((+/-)-trans-6-[Ethyl-(2-methoxybenzyl)amino]hexano...)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed