Compile Data Set for Download or QSAR
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Found 98 Enz. Inhib. hit(s) with all data for entry = 50027752
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273814(6-Isoquinolin-4-yl-1-methyl-3,4-dihydroquinolin-2(...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273781(6-(5-methoxypyridin-3-yl)-1-methyl-3,4-dihydroquin...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273813(6-Isoquinolin-4-yl-3,4-dihydroquinolin-2(1H)-one |...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273700(6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitri...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273776(1-Methyl-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273780(6-(5-Methoxypyridin-3-yl)-3,4-dihydroquinolin-2(1H...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273815(6-Pyridin-3-yl-3,4-dihydroquinoline-2(1H)-thione |...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273778(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273816(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinoline-2(1H)...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273679(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalene-2-car...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273814(6-Isoquinolin-4-yl-1-methyl-3,4-dihydroquinolin-2(...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273817(7-Pyridin-3-yl-2H-1,4-benzothiazin-3(4H)-one | CHE...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273706(5-Pyridin-3-yl-1,3-dihydro-2H-indol-2-one | CHEMBL...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273777(1-Ethyl-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-o...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50000306(6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | 6-P...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273675(3-(5,6,7,8-Tetrahydronaphthalen-2-yl)pyridine | CH...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273678(3-(6-Ethoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyri...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273813(6-Isoquinolin-4-yl-3,4-dihydroquinolin-2(1H)-one |...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273676(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol |...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273779(8-Nitro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-o...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273781(6-(5-methoxypyridin-3-yl)-1-methyl-3,4-dihydroquin...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273701(4-Methyl-7-pyridin-3-yl-3,4-dihydro-2H-1,4-benzoxa...)
Affinity DataIC50:  101nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273702(3-(2,3-Dihydro-1,4-benzodioxin-6-yl)pyridine | CHE...)
Affinity DataIC50:  154nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273700(6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitri...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50:  191nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273700(6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitri...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273780(6-(5-Methoxypyridin-3-yl)-3,4-dihydroquinolin-2(1H...)
Affinity DataIC50:  339nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273817(7-Pyridin-3-yl-2H-1,4-benzothiazin-3(4H)-one | CHE...)
Affinity DataIC50:  525nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273815(6-Pyridin-3-yl-3,4-dihydroquinoline-2(1H)-thione |...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM8905(3-(6-Methoxy-2-naphthyl)pyridine | 3-(6-methoxynap...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human placental CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273676(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol |...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273678(3-(6-Ethoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyri...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273815(6-Pyridin-3-yl-3,4-dihydroquinoline-2(1H)-thione |...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273679(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalene-2-car...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273776(1-Methyl-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50:  742nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273679(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalene-2-car...)
Affinity DataIC50:  745nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273816(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinoline-2(1H)...)
Affinity DataIC50:  769nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50:  819nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273703(6-Pyridin-3-yl-3,4-dihydronaphthalen-2(1H)-one | C...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273704(5-Pyridin-3-yl-2,3-dihydro-1H-inden-1-one | CHEMBL...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273705(6-(5-Methoxypyridin-3-yl)-3,4-dihydronaphthalen-2(...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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