Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50027797
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246648((R)-1-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylac...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50005530(CHEMBL267633 | D-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-G...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50060728((R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-hyd...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50060728((R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-hyd...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]propionyl-pNPY from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246647((R)-ethyl (5-(4-hydroxybenzylamino)-4-(2,2-dipheny...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]propionyl-pNPY from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246613((R)-N-(4-hydroxybenzyl)-5-(2-acetylguanidino)-2-(2...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]propionyl-pNPY from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246615((R)-N-(4-hydroxybenzyl)-2-(2,2-diphenylacetamido)-...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]propionyl-pNPY from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246614((R)-methyl (5-(4-hydroxybenzylamino)-4-(2,2-diphen...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]propionyl-pNPY from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of Dy-635-pNPY from human neuropeptide Y5 receptor expressed in HEC-1B cells by flow cytometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of Cy5-[K4]-hPP from human neuropeptide Y4 receptor expressed in CHO cells coexpressing Galphaqi5 and aequorin by flow cytometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of Dy-635-pNPY from human neuropeptide Y2 receptor expressed in CHO cells coexpressing Galphaqi5 and aequorin by flow cytometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human MCF7 cells by kinetic experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human SK-N-MC cells by kinetic experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.20nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed