Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50028623
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)
Affinity DataKd:  70nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataKd:  110nMAssay Description:Binding affinity to human PARP1 by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM27533(4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)pht...)
Affinity DataKd:  19nMAssay Description:Binding affinity to human PARP1 by isothermal titration colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50277614(2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]py...)
Affinity DataKd:  200nMAssay Description:Binding affinity to human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50277614(2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]py...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50226518(3-Aminobenzoesaeure | 3-aminobenzoic acid | CHEMBL...)
Affinity DataKd: >2.00E+3nMAssay Description:Binding affinity to human PARP3 PARP domain by isothermal titration colorimetryMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Institutet

Curated by ChEMBL
LigandPNGBDBM50277614(2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]py...)
Affinity DataKd:  150nMAssay Description:Binding affinity to human PARP1 by isothermal titration colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed