Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50033462
TargetAcetylcholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345813(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((S)-1-p...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  179nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345812(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...)
Affinity DataIC50:  302nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345813(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((S)-1-p...)
Affinity DataIC50:  334nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345810(3-((S)-1-(dimethylamino)ethyl)phenyl(R)-1-phenylpr...)
Affinity DataIC50:  404nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345810(3-((S)-1-(dimethylamino)ethyl)phenyl(R)-1-phenylpr...)
Affinity DataIC50:  416nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345811(3-((S)-1-(dimethylamino)ethyl)phenyl(S)-1-phenylpr...)
Affinity DataIC50:  508nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  2.62E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345811(3-((S)-1-(dimethylamino)ethyl)phenyl(S)-1-phenylpr...)
Affinity DataIC50:  7.32E+3nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Sention

Curated by ChEMBL
LigandPNGBDBM50345812(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed