Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50030428
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296002(CHEMBL564536 | isopropyl 3-chloro-5-(1-(6-(2-(5-et...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296002(CHEMBL564536 | isopropyl 3-chloro-5-(1-(6-(2-(5-et...)
Affinity DataIC50:  36nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295987(CHEMBL564513 | N-ethyl-6-(2-(5-ethyl-4-methyloxazo...)
Affinity DataIC50:  400nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295989(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50:  480nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295990(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-isoprop...)
Affinity DataIC50:  540nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295988(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-methyl-...)
Affinity DataIC50:  830nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295991(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-(2-meth...)
Affinity DataIC50:  900nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295994(CHEMBL562831 | ethyl 2-(6-(2-(5-ethyl-4-methyloxaz...)
Affinity DataIC50:  910nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295996(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295993(3-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295992(2-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50:  4.30E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295996(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50:  4.30E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295995(CHEMBL559987 | N-(6-(2-(5-ethyl-4-methyloxazol-2-y...)
Affinity DataIC50:  7.00E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295997(2-(6-((5-ethyl-4-methyloxazol-2-ylthio)methyl)-4-m...)
Affinity DataIC50:  8.30E+3nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295989(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morphol...)
Affinity DataIC50:  9.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295998(2-(6-((4,5-dimethyloxazol-2-ylthio)methyl)-4-morph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296000(2-(4-morpholino-6-((1,4,5-trimethyl-1H-imidazol-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296001(2-(6-((4,5-dimethylthiazol-2-ylthio)methyl)-4-morp...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [35S]MK499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295991(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-(2-meth...)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296001(2-(6-((4,5-dimethylthiazol-2-ylthio)methyl)-4-morp...)
Affinity DataIC50:  1.50E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295994(CHEMBL562831 | ethyl 2-(6-(2-(5-ethyl-4-methyloxaz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295987(CHEMBL564513 | N-ethyl-6-(2-(5-ethyl-4-methyloxazo...)
Affinity DataIC50:  1.60E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295997(2-(6-((5-ethyl-4-methyloxazol-2-ylthio)methyl)-4-m...)
Affinity DataIC50:  2.10E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295992(2-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50:  2.10E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295993(3-(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-4-morp...)
Affinity DataIC50:  2.20E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295990(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-isoprop...)
Affinity DataIC50:  2.50E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295988(6-(2-(5-ethyl-4-methyloxazol-2-yl)ethyl)-N-methyl-...)
Affinity DataIC50:  3.20E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296000(2-(4-morpholino-6-((1,4,5-trimethyl-1H-imidazol-2-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295998(2-(6-((4,5-dimethyloxazol-2-ylthio)methyl)-4-morph...)
Affinity DataIC50:  7.00E+4nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295995(CHEMBL559987 | N-(6-(2-(5-ethyl-4-methyloxazol-2-y...)
Affinity DataIC50:  3.20E+5nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295999(2-(6-((4,5-dimethyloxazol-2-yloxy)methyl)-4-morpho...)
Affinity DataIC50: >1.00E+6nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y1 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding by scinitill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed