Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50030435
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296117(2-(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amino)hex...)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296119(2,5-bis(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50:  1.55nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50:  4.03nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50:  958nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296117(2-(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amino)hex...)
Affinity DataIC50:  982nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296119(2,5-bis(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50:  7.91E+3nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296119(2,5-bis(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50:  9.34E+3nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296117(2-(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amino)hex...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50:  2.83E+4nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed