Compile Data Set for Download or QSAR
maximum 50k data
Found 79 Enz. Inhib. hit(s) with all data for entry = 50030746
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300820(CHEMBL565723 | N-(2-{3-[(3-Chlorophenyl)sulfonyl]-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300845(CHEMBL565746 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300842(CHEMBL565724 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300843(CHEMBL565976 | N-(2-{3-[(3-Fluorophenyl)sulfonyl]-...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300839(2-[3-(1-Naphthylsulfonyl)-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300824(2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300833(2-(3-{[2-(Trifluoromethyl)phenyl]sulfonyl}-1Hpyrro...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300834(2-(3-{[3-(Trifluoromethyl)phenyl]sulfonyl}-1Hpyrro...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300825(CHEMBL584046 | N,N-Dimethyl-N-(2-{3-[(3-chlorophen...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300836(2-{3-[(3,5-Dichlorophenyl)sulfonyl]-1H-pyrrolo[2,3...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300841(CHEMBL583389 | N-(2-{3-[(5-Chlorothien-2-yl)sulfon...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300830(2-[2-Methyl-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]py...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300835(CHEMBL565977 | N-(2-{3-[(3,5-Dichlorophenyl)sulfon...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300827(2-{3-[(3-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300829(CHEMBL565730 | N,N-Dimethyl-N-{2-[2-methyl-3-(phen...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300828(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300831(2-[3-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-y...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300837(CHEMBL568249 | N-(2-{3-[(2,6-Dichlorophenyl)sulfon...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300844(CHEMBL568673 | N-(2-{3-[(2,5-Dichlorophenyl)sulfon...)
Affinity DataKi:  11.7nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300840(CHEMBL565753 | N,N-Dimethyl-N-{2-[3-(thien-2-ylsul...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50155128(CHEMBL183203 | N,N-dimethyl-2-(3-(phenylsulfonyl)-...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300821(2-{3-[(4-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300832(CHEMBL578826 | N,N-Dimethyl-N-{2-[3-(phenylsulfony...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50155140(2-(3-(phenylsulfonyl)-1H-indol-1-yl)ethanamine | 2...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300822(CHEMBL579063 | N,N-Dimethyl-N-(2-{3-[(4-fluorophen...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300823(3-[(3-Chlorophenyl)sulfonyl]-1-(2-pyrrolidin-1-yle...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300826(3-[(3-Fluorophenyl)sulfonyl]-1-(2-pyrrolidin-1-yle...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300845(CHEMBL565746 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...)
Affinity DataIC50:  5.40nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as inhibition of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300843(CHEMBL565976 | N-(2-{3-[(3-Fluorophenyl)sulfonyl]-...)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as inhibition of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300820(CHEMBL565723 | N-(2-{3-[(3-Chlorophenyl)sulfonyl]-...)
Affinity DataIC50:  8.30nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as inhibition of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300824(2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]DOI from human cloned 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300844(CHEMBL568673 | N-(2-{3-[(2,5-Dichlorophenyl)sulfon...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as inhibition of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300824(2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  44nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300825(CHEMBL584046 | N,N-Dimethyl-N-(2-{3-[(3-chlorophen...)
Affinity DataIC50:  131nMAssay Description:Displacement of [125I]DOI from human cloned 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300828(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  351nMAssay Description:Displacement of [125I]DOI from human cloned 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300825(CHEMBL584046 | N,N-Dimethyl-N-(2-{3-[(3-chlorophen...)
Affinity DataIC50:  477nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...)
Affinity DataIC50:  511nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300828(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  644nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...)
Affinity DataIC50:  938nMAssay Description:Displacement of [125I]DOI from human cloned 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...)
Affinity DataIC50:  1.14E+3nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300825(CHEMBL584046 | N,N-Dimethyl-N-(2-{3-[(3-chlorophen...)
Affinity DataIC50:  1.22E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300824(2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  1.36E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...)
Affinity DataIC50:  1.56E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300828(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  4.76E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300828(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: >5.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300831(2-[3-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-y...)
Affinity DataIC50: >5.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300838(CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...)
Affinity DataIC50: >5.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300824(2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50: >5.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300825(CHEMBL584046 | N,N-Dimethyl-N-(2-{3-[(3-chlorophen...)
Affinity DataIC50: >5.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 79 total ) | Next | Last >>
Jump to: