Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50030806
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301753(CHEMBL565728 | isopropyl 2-cyano-6-(3,4-difluorobe...)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301769(CHEMBL576636 | isopropyl 2-cyano-4,4-dimethyl-6-(t...)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301755(CHEMBL578150 | isopropyl 2-cyano-6-(4-fluorobenzoy...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301756(CHEMBL568235 | isopropyl 2-cyano-6-(cyclohexanecar...)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301757(CHEMBL571961 | isopropyl 2-cyano-6-(4-cyanobenzoyl...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301758(CHEMBL578757 | isopropyl 6-(3-chlorobenzoyl)-2-cya...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301759(CHEMBL576415 | isopropyl 2-cyano-4,4-dimethyl-6-(3...)
Affinity DataEC50:  8.5nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301760(CHEMBL578756 | isopropyl 2-cyano-4,4-dimethyl-6-(t...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301761(CHEMBL568014 | isopropyl 2-cyano-6-(3,4-difluorobe...)
Affinity DataEC50:  280nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301762(CHEMBL584048 | isopropyl 2-cyano-6-(3-fluorobenzoy...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301763(CHEMBL565729 | isopropyl 2-cyano-6-(4-fluorobenzoy...)
Affinity DataEC50:  640nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301764(CHEMBL579197 | isopropyl 2-cyano-6-(cyclohexanecar...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301765(CHEMBL579263 | isopropyl 2-cyano-6-(4-cyanobenzoyl...)
Affinity DataEC50:  5.70E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301766(CHEMBL565752 | isopropyl 6-(3-chlorobenzoyl)-2-cya...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301767(CHEMBL565981 | isopropyl 2-cyano-4,4-dimethyl-6-(3...)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301768(CHEMBL584897 | isopropyl 6-(4-chlorobenzoyl)-2-cya...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301754(CHEMBL578970 | isopropyl 2-cyano-6-(3-fluorobenzoy...)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed