Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with all data for entry = 8091
TargetcDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universidad Nacional Autonoma De Mexico

LigandPNGBDBM233039(Finasteride (3))
Affinity DataIC50:  8.5nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universidad Nacional Autonoma De Mexico

LigandPNGBDBM233040(17α-Acetoxyprogesterone (6))
Affinity DataIC50:  10nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universidad Nacional Autonoma De Mexico

LigandPNGBDBM233043(6-Chloro-3,20-dioxopregna-4,6-diene-17α-yl ac...)
Affinity DataIC50:  19nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universidad Nacional Autonoma De Mexico

LigandPNGBDBM233042(3,20-Dioxo-6,7-epoxypregn-4-ene-7α-yl acetate...)
Affinity DataIC50:  22nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universidad Nacional Autonoma De Mexico

LigandPNGBDBM233041(3,20-Dioxopregna-4,6-dien-17α-yl acetate (7))
Affinity DataIC50:  70nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed