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Found 11 Enz. Inhib. hit(s) with all data for entry = 50039028
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304655((4R,6S)-6-[(E)-2-(2-cyclopropyl-6-fluoro-4-(3-meth...)
Affinity DataIC50:  5.61E+3nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304654((4R,6S)-6-[(E)-2-(2-cyclopropyl-6-fluoro-4-(4-fluo...)
Affinity DataIC50:  6.93E+3nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304661(4R,6S)-6-[(E)-2-(2-cyclopropyl-6-fluoro-4,7-di(3-m...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50371229(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304653((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-isopropylphen...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304656((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenylt...)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304657((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-isopropylphen...)
Affinity DataIC50:  4.13E+4nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304660((4R,6S)-6-((E)-2-(2-cyclopropyl-6-fluoro-4,7-bis(4...)
Affinity DataIC50:  4.57E+4nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304652((4R,6S)-6-[(E)-2-[2-Cyclopropyl-4-(4-fluorothiophe...)
Affinity DataIC50:  6.24E+4nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304658((4R,6S)-6-((E)-2-(2-cyclopropyl-6,7-difluoro-4-(3-...)
Affinity DataIC50:  3.60E+5nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50304659((4R,6S)-6-((E)-2-(2-cyclopropyl-6,7-difluoro-4-(4-...)
Affinity DataIC50:  7.59E+5nMAssay Description:Inhibition of HMG CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed