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Found 14 Enz. Inhib. hit(s) with all data for entry = 50031382
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312519(CHEMBL1089385 | [3,4-Dioxo-10-(4-phenoxycarbonylme...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50107141((10-Benzyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imi...)
Affinity DataIC50:  360nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  620nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312515(CHEMBL1093738 | [3,4-Dioxo-10-(4-trichloromethyl-b...)
Affinity DataIC50:  4.24E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312510(CHEMBL1083200 | [10-(4-Hydroxy-benzyl)-3,4-dioxo-3...)
Affinity DataIC50:  4.56E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312514(CHEMBL1093737 | [10-(4-Bromo-benzyl)-3,4-dioxo-3,4...)
Affinity DataIC50:  4.76E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312518(CHEMBL1092151 | [10-(2,4-Difluoro-benzyl)-3,4-diox...)
Affinity DataIC50:  8.22E+3nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312511(CHEMBL1085681 | [10-(4-Bromo-2-chloro-benzyl)-3,4-...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312517(CHEMBL1092150 | [10-(3,5-Dinitro-benzyl)-3,4-dioxo...)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312512(CHEMBL1085682 | [10-(4-Amino-benzyl)-3,4-dioxo-3,4...)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312516(CHEMBL1094044 | [10-(4-Chloro-2-fluoro-benzyl)-3,4...)
Affinity DataIC50:  3.65E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312513(CHEMBL1085913 | [10-(4-Dimethylamino-benzyl)-3,4-d...)
Affinity DataIC50:  3.84E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Institute Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50312509((10-Ethyl-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imid...)
Affinity DataIC50:  4.24E+4nMAssay Description:Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed